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oai:repisalud.isciii.es:20.500.12105/173652024-09-27T15:34:53Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19612

00925njm 22002777a 4500 dc Bouza, Carmen author Lopez-Cuadrado, Teresa author Magro, Angeles author Navalpotro, Lourdes author Amate, Jose Maria author 2006-07 The aim of this study is to evaluate the efficacy and safety of balloon kyphoplasty (BK) in the management of vertebral compression fractures (VCFs). This study is based on a systematic review of the literature (until October 2004) and meta-analysis of clinical studies assessing the efficacy and safety of BK in the treatment of VCFs. Estimates of effect were based on a random effects model. Meta-regression analyses were carried out where required. A total of 26 studies met the inclusion criteria. Although studies displayed considerable methodological limitations, the results of the clinical series indicate significant improvements in pain intensity, vertebral height, sagittal alignment, functional capacity, and quality of life. Compared with conventional medical management, BK afforded significant improvement in pain intensity and mobility. Likewise, a significant reduction was observed in vertebral collapse, kyphotic deformity, the development of new vertebral fractures, and hospital stay. Compared with vertebroplasty, the technique reduced the loss of height and the degree of kyphotic deformity, and afforded a significantly lower leakage rate-with no differences in relation to other variables. Regarding adverse effects, leakage affected 7% of all levels treated, while complications were recorded in 2% of the patients, and new vertebral fractures in 16%. The available evidence suggests that BK can be effective and safe in application to VCFs. However, existing studies evince substantial methodological limitations and relatively short follow-up periods. Better clinical research is required to determine the capacity of BK to avoid the functional and physiological sequelae of VCFs and to define the true role of the technique among the existing therapeutic options. Eur Spine J. 2006 Jul;15(7):1050-67. 10.1007/s00586-005-0048-x 0940-6719 European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233932/pdf/586_2005_Article_48.pdf 16429288 http://hdl.handle.net/20.500.12105/17365 Balloon kyphoplasty Evidence Meta-analysis Vertebral compression fractures Efficacy and safety of balloon kyphoplasty in the treatment of vertebral compression fractures: a systematic review