2026-06-14T03:41:08Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/173432024-01-23T20:13:15Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927
Repisalud
author
Villatoro, Antonio J
author
Fernández, Viviana
author
Claros, Silvia
author
Alcoholado, Cristina
author
Cifuentes, Manuel
author
Merayo-Lloves, Jesús
author
Andrades, José A
author
Becerra, José
authoraffiliation
[Villatoro, Antonio J.] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Fernandez, Viviana] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Claros, Silvia] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Alcoholado, Cristina] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Cifuentes, Manuel] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Andrades, Jose A.] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Becerra, Jose] Univ Malaga, Dept Cell Biol Genet & Physiol, IBIMA, Malaga, Spain
authoraffiliation
[Claros, Silvia] CIBER, BBN, Networking Res Ctr Bioengn Biomat & Nanomed, Malaga, Spain
authoraffiliation
[Alcoholado, Cristina] CIBER, BBN, Networking Res Ctr Bioengn Biomat & Nanomed, Malaga, Spain
authoraffiliation
[Cifuentes, Manuel] CIBER, BBN, Networking Res Ctr Bioengn Biomat & Nanomed, Malaga, Spain
authoraffiliation
[Andrades, Jose A.] CIBER, BBN, Networking Res Ctr Bioengn Biomat & Nanomed, Malaga, Spain
authoraffiliation
[Becerra, Jose] CIBER, BBN, Networking Res Ctr Bioengn Biomat & Nanomed, Malaga , Spain
authoraffiliation
[Merayo-Lloves, Jesus] Fdn Invest Oftalmol, Oviedo, Spain
authoraffiliation
[Becerra, Jose] Andalusian Ctr Nanomed & Biotechnol BIONAND, Lab Bioingn & Tissue Regenerat, Malaga, Spain
2024-01-23T20:13:15Z
2024-01-23T20:13:15Z
2017-10-28
10.3390/ijms18112264
1422-0067
International journal of molecular sciences
http://hdl.handle.net/10668/11803
29143779
http://hdl.handle.net/20.500.12105/17343
Dry eye syndrome is a complex and insidious pathology with a high level of prevalence among the human population and with a consequently high impact on quality of life and economic cost. Currently, its treatment is symptomatic, mainly based on the control of lubrication and inflammation, with significant limitations. Therefore, the latest research is focused on the development of new biological strategies, with the aim of regenerating affected tissues, or at least restricting the progression of the disease, reducing scar tissue, and maintaining corneal transparency. Therapies range from growth factors and cytokines to the use of different cell sources, in particular mesenchymal stem cells, due to their multipotentiality, trophic, and immunomodulatory properties. We will review the state of the art and the latest advances and results of these promising treatments in this pathology.
eng
allogenic cell therapy
dry eye
growth factor
keratoconjunctivitis sicca
lacrimal gland
mesenchymal stem cell
regenerative medicine
Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy.
research article