2026-08-29T14:17:39Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/172852024-11-28T15:01:46Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16967col_20.500.12105_16973
Repisalud
author
Romero-Sanchiz, Pablo
author
Nogueira-Arjona, Raquel
author
García-Ruiz, Antonio
author
Luciano, Juan V
author
García Campayo, Javier
author
Gili, Margalida
author
Botella, Cristina
author
Baños, Rosa
author
Castro, Adoración
author
López-Del-Hoyo, Yolanda
author
Pérez Ara, Mª Ángeles
author
Modrego-Alarcón, Marta
author
Mayoral Cleríes, Fermín
authoraffiliation
[Romero-Sanchiz,P; Mayoral Cleríes,F] Mental Health Clinical Management Unit, Institute of Biomedical Research of Malaga (IBIMA), Regional University Hospital Carlos Haya, Malaga, Spain. [Nogueira-Arjona,R] Department of Personality, Assessment and Psychological Treatments, Faculty of Psychology, University of Malaga, Malaga, Spain. [García-Ruiz,A] Chair of Health Economics and Rational Drug Use. Department of Pharmacology and Pediatrics, Faculty of Medicine, University of Malaga, Malaga, Spain. [Luciano,JV] Teaching, Research & Innovation Unit, Parc Sanitari Sant Joan de Déu, St. Boi de Llobregat, Spain. [Luciano,JV; García Campayo,J; Gili,M; Castro,A, López-Del-Hoyo,Y; Pérez Ara,MA; Mayoral Cleríes,F] Primary Care Prevention and Health Promotion Research Network, RedIAPP, Madrid, Spain. [García Campayo,J; López-Del-Hoyo,Y] Aragon Institute for Health Research (IIS Aragon), Zaragoza, Spain. [García Campayo,J] University Hospital Miguel Servet, Zaragoza, Spain. [Gili,M; Castro,A; Pérez Ara,MA] IUNICS-IDISPA, University of Balearic Islands, Palma de Mallorca, Spain. [ Botella,C] University Jaume I, Castellon de la Plana, Spain. [Botella,C; Baños,R] CIBER Physiopathology Obesity and Nutrition (CB06/03) Carlos III Health Institute, Madrid, Spain. [Baños,R] University of Valencia, Valencia, Spain. [López-Del-Hoyo,Y; Modrego-Alarcón,M] University of Zaragoza, Zaragoza, Spain. [Modrego-Alarcón,M] Foundation Institute of Health Research of Aragon (IIS Aragon), Zaragoza, Spain.
2024-01-23T20:12:23Z
2024-01-23T20:12:23Z
2017-02
10.1371/journal.pone.0172741
1932-6203
PloS One
http://hdl.handle.net/10668/2677http://hdl.handle.net/20.500.13003/9943
28241025
L614571055
2-s2.0-85014090413
http://hdl.handle.net/20.500.12105/17285
395934400035
Depression is one of the most common mental disorders and will become one of the leading causes of disability in the world. Internet-based CBT programs for depression have been classified as "well established" following the American Psychological Association criteria for empirically supported treatments. The aim of this study is to analyze the cost effectiveness at 12-month follow-up of the Internet-based CBT program "Smiling is fun" with (LITG) and without psychotherapist support (TSG) compared to usual care. The perspective used in our analysis is societal. A sample of 296 depressed patients (mean age of 43.04 years; 76% female; BDI-II mean score = 22.37) from primary care services in four Spanish regions were randomized in the RCT. The complete case and intention-to-treat (ITT) perspectives were used for the analyses. The results demonstrated that both Internet-based CBT interventions exhibited cost utility and cost effectiveness compared with a control group. The complete case analyses revealed an incremental cost-effectiveness ratio (ICER) of €-169.50 and an incremental cost-utility ratio (ICUR) of €-11389.66 for the TSG group and an ICER of €-104.63 and an ICUR of €-6380.86 for the LITG group. The ITT analyses found an ICER of €-98.37 and an ICUR of €-5160.40 for the TSG group and an ICER of €-9.91 and an ICUR of €496.72 for the LITG group. In summary, the results of this study indicate that the two Internet-based CBT interventions are appropriate from both economic and clinical perspectives for depressed patients in the Spanish primary care system. These interventions not only help patients to improve clinically but also generate societal savings.
eng
Adulto
Grupos control
Análisis costo-beneficio
Depresión
Trastorno depresivo
Femenino
Estudios de seguimiento
Hispanoamericanos
Humanos
Análisis de intención de tratar
Internet
Atención primaria de salud
Psicoterapia
Sonrisa
Sociedades científicas
Economic evaluation of a guided and unguided internet-based CBT intervention for major depression: Results from a multi-center, three-armed randomized controlled trial conducted in primary care.
research article