2026-05-22T00:05:36Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/172852024-11-28T15:01:46Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927col_20.500.12105_16967col_20.500.12105_16973

00925njm 22002777a 4500 dc Romero-Sanchiz, Pablo author Nogueira-Arjona, Raquel author García-Ruiz, Antonio author Luciano, Juan V author García Campayo, Javier author Gili, Margalida author Botella, Cristina author Baños, Rosa author Castro, Adoración author López-Del-Hoyo, Yolanda author Pérez Ara, Mª Ángeles author Modrego-Alarcón, Marta author Mayoral Cleríes, Fermín author 2017-02 Depression is one of the most common mental disorders and will become one of the leading causes of disability in the world. Internet-based CBT programs for depression have been classified as "well established" following the American Psychological Association criteria for empirically supported treatments. The aim of this study is to analyze the cost effectiveness at 12-month follow-up of the Internet-based CBT program "Smiling is fun" with (LITG) and without psychotherapist support (TSG) compared to usual care. The perspective used in our analysis is societal. A sample of 296 depressed patients (mean age of 43.04 years; 76% female; BDI-II mean score = 22.37) from primary care services in four Spanish regions were randomized in the RCT. The complete case and intention-to-treat (ITT) perspectives were used for the analyses. The results demonstrated that both Internet-based CBT interventions exhibited cost utility and cost effectiveness compared with a control group. The complete case analyses revealed an incremental cost-effectiveness ratio (ICER) of €-169.50 and an incremental cost-utility ratio (ICUR) of €-11389.66 for the TSG group and an ICER of €-104.63 and an ICUR of €-6380.86 for the LITG group. The ITT analyses found an ICER of €-98.37 and an ICUR of €-5160.40 for the TSG group and an ICER of €-9.91 and an ICUR of €496.72 for the LITG group. In summary, the results of this study indicate that the two Internet-based CBT interventions are appropriate from both economic and clinical perspectives for depressed patients in the Spanish primary care system. These interventions not only help patients to improve clinically but also generate societal savings. 10.1371/journal.pone.0172741 1932-6203 PloS One http://hdl.handle.net/10668/2677 http://hdl.handle.net/20.500.13003/9943 28241025 L614571055 2-s2.0-85014090413 http://hdl.handle.net/20.500.12105/17285 395934400035 Adulto Grupos control Análisis costo-beneficio Depresión Trastorno depresivo Femenino Estudios de seguimiento Hispanoamericanos Humanos Análisis de intención de tratar Internet Atención primaria de salud Psicoterapia Sonrisa Sociedades científicas Economic evaluation of a guided and unguided internet-based CBT intervention for major depression: Results from a multi-center, three-armed randomized controlled trial conducted in primary care.