2026-08-05T15:46:04Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/171352024-01-16T12:16:09Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927
Repisalud
author
García-Cortés, Miren
author
Robles-Díaz, Mercedes
author
Ortega-Alonso, Aida
author
Medina-Caliz, Inmaculada
author
Andrade, Raul J
2024-01-16T12:16:09Z
2024-01-16T12:16:09Z
2016-04-09
10.3390/ijms17040537
1422-0067
International journal of molecular sciences
http://hdl.handle.net/10668/9989
27070596
http://hdl.handle.net/20.500.12105/17135
Dietary supplements (DS) are extensively consumed worldwide despite unproven efficacy. The true incidence of DS-induced liver injury (DSILI) is unknown but is probably under-diagnosed due to the general belief of safety of these products. Reported cases of herbals and DS-induced liver injury are increasing worldwide. The aim of this manuscript is to report a tabular listing with a description of DS associated with hepatotoxicity as well as review the phenotype and severity of DSILI. Natural remedies related to hepatotoxicity can be divided into herbal product-induced liver injury and DS-induced liver injury. In this article, we describe different DS associated with liver injury, some of them manufactured DS containing several ingredients (Herbalife™ products, Hydroxycut™, LipoKinetix™, UCP-1 and OxyELITE™) while others have a single ingredient (green tea extract, linoleic acid, usnic acid, 1,3-Dimethylamylamine, vitamin A, Garcinia cambogia and ma huang). Additional DS containing some of the aforementioned ingredients implicated in liver injury are also covered. We have also included illicit androgenic anabolic steroids for bodybuilding in this work, as they are frequently sold under the denomination of DS despite being conventional drugs.
eng
Herbalife products
Hydroxycut
Oxyelite Pro
anabolic steroids
dietary supplements
green tea
hepatotoxicity
liver injury
usnic acid
vitamin A
Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics.
research article