2026-04-29T17:02:14Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/170572024-11-28T15:34:29Zcom_20.500.12105_15322com_20.500.12105_2051col_20.500.12105_16927
Repisalud
author
Ramírez-Bueno, A
author
Salazar-Ramírez, C
author
Cota-Delgado, F
author
Torre-Prados, M V de la
author
Valdivielso, P
authoraffiliation
[Ramírez-Bueno,A; Valdivielso,P] Unidad de Gestión Clínica de Medicina Interna, Instituto de Biomedicina de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Salazar-Ramírez,C; Cota-Delgado,F; Torre-Prados,M V de la] Unidad de Gestión Clínica de Cuidados Críticos y Urgencias, Instituto de Biomedicina de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Valdivielso,P] Unidad de Gestión Clínica de Cuidados Críticos y Urgencias, Instituto de Biomedicina de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Spain.
2024-01-15T18:17:05Z
2024-01-15T18:17:05Z
2014-02
10.1016/j.ejim.2013.08.701
1879-0828
0953-6205
European journal of internal medicine
http://hdl.handle.net/10668/1874
24012324
http://hdl.handle.net/20.500.12105/17057
BACKGROUND: Severe hypertriglyceridemia with an accumulation of chylomicrons and triglyceride figures >1000 mg/dL can cause acute pancreatitis, a potentially fatal complication. The option of rapid reduction in triglyceride concentrations is attractive and possible with plasmapheresis. METHODS: We present the results of an analysis of 11 patients admitted to the intensive care unit with severe hypertriglyceridemic pancreatitis and treated with plasmapheresis. The procedure was repeated until serum triglycerides were below 1000 mg/dL. We recorded anthropometric, clinical data as well as final outcome. RESULTS: In eight patients a single plasma exchange was sufficient to reduce triglyceride figures <1000 mg/dL. Only three patients died, all with the worst severity indexes and who experienced the longest delay before the procedure. CONCLUSIONS: Our results, together with a review of the literature, confirm the need for a randomized clinical trial to compare conventional treatment vs. plasmapheresis in patients with severe hypertriglyceridemic pancreatitis.
eng
Plasmapheresis
Acute pancreatitis
Hypertriglyceridemic pancreatitis
Severe hypertriglyceridemia
Plasmaféresis
Pancreatitis
Hiperlipidemias
Enfermedad aguda
Índice de severidad de la enfermedad
Resultado del tratamiento
Plasmapheresis as treatment for hyperlipidemic pancreatitis.
research article