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00925njm 22002777a 4500 dc Portillo-Van Diest, Ana author Vilagut, Gemma author Alayo, Itxaso author Ferrer, Montse author Amigo, Franco author Amann, Benedikt L author Aragón-Peña, Andrés author Aragonès, Enric author Asúnsolo-Del-Barco, Ángel author Campos, Mireia author Del Cura-González, Isabel author Espuga, Meritxell author González-Pinto, Ana author Haro, Josep Maria author Larrauri, Amparo author López-Fresneña, Nieves author Martínez de Salázar, Alma author Molina, Juan D author Ortí-Lucas, Rafael M author Parellada, Mara author Pelayo-Terán, José María author Pérez-Zapata, Aurora author Pijoan, José I author Plana, Nieves author Puig, Teresa author Rius, Cristina author Rodriguez-Blazquez, Carmen author Sanz, Ferran author Serra, Consol author Urreta-Barallobre, Iratxe author Kessler, Ronald C author Bruffaerts, Ronny author Vieta, Eduard author Pérez-Solá, Víctor author Alonso, Jordi author Mortier, Philippe author MINDCOVID Working Group author 2023-08-09 Aim: To investigate the occurrence of traumatic stress symptoms (TSS) among healthcare workers active during the COVID-19 pandemic and to obtain insight as to which pandemic-related stressful experiences are associated with onset and persistence of traumatic stress. Methods: This is a multicenter prospective cohort study. Spanish healthcare workers (N = 4,809) participated at an initial assessment (i.e., just after the first wave of the Spain COVID-19 pandemic) and at a 4-month follow-up assessment using web-based surveys. Logistic regression investigated associations of 19 pandemic-related stressful experiences across four domains (infection-related, work-related, health-related and financial) with TSS prevalence, incidence and persistence, including simulations of population attributable risk proportions (PARP). Results: Thirty-day TSS prevalence at T1 was 22.1%. Four-month incidence and persistence were 11.6% and 54.2%, respectively. Auxiliary nurses had highest rates of TSS prevalence (35.1%) and incidence (16.1%). All 19 pandemic-related stressful experiences under study were associated with TSS prevalence or incidence, especially experiences from the domains of health-related (PARP range 88.4-95.6%) and work-related stressful experiences (PARP range 76.8-86.5%). Nine stressful experiences were also associated with TSS persistence, of which having patient(s) in care who died from COVID-19 had the strongest association. This association remained significant after adjusting for co-occurring depression and anxiety. Conclusions: TSSs among Spanish healthcare workers active during the COVID-19 pandemic are common and associated with various pandemic-related stressful experiences. Future research should investigate if these stressful experiences represent truly traumatic experiences and carry risk for the development of post-traumatic stress disorder. Epidemiol Psychiatr Sci. 2023 Aug 9:32:e50. 10.1017/S2045796023000628 2045-7979 Epidemiology and psychiatric sciences 37555258 http://hdl.handle.net/20.500.12105/16787 COVID-19 Health personnel Prospective cohort study Traumatic stress Traumatic stress symptoms among Spanish healthcare workers during the COVID-19 pandemic: a prospective study