2026-05-22T00:53:47Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/164052024-05-27T19:32:33Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Cuartero, María Isabel
author
García-Culebras, Alicia
author
Nieto-Vaquero, Carmen
author
Fraga, Enrique
author
Torres-López, Cristina
author
Pradillo, Jesús
author
Lizasoain, Ignacio
author
Moro, María Ángeles
funder
Instituto de Salud Carlos III
funder
Fondation Leducq
funder
Ministerio de Ciencia e Innovación (España)
2023-09-05T08:24:59Z
2023-09-05T08:24:59Z
2023-06-16
Br J Pharmacol. 2023 Jun 16.
10.1111/bph.16167
1476-5381
British journal of pharmacology
37328270
http://hdl.handle.net/20.500.12105/16405
In recent years, increasing evidence suggests that commensal microbiota may play an important role not only in health but also in disease including cerebrovascular disease. Gut microbes impact physiology, at least in part, by metabolizing dietary factors and host-derived substrates and then generating active compounds including toxins. The purpose of this current review is to highlight the complex interplay between microbiota, their metabolites. and essential functions for human health, ranging from regulation of the metabolism and the immune system to modulation of brain development and function. We discuss the role of gut dysbiosis in cerebrovascular disease, specifically in acute and chronic stroke phases, and the possible implication of intestinal microbiota in post-stroke cognitive impairment and dementia, and we identify potential therapeutic opportunities of targeting microbiota in this context.
eng
The role of gut microbiota in cerebrovascular disease and related dementia.
review
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The role of gut microbiota in cerebrovascular_Br J Pharmacol_2023.pdf
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https://repisalud.isciii.es/bitstreams/774165a4-de09-43b7-84fe-26bf00e7dc22/download
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The role of gut microbiota in cerebrovascular_Br J Pharmacol_2023.pdf.txt