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oai:repisalud.isciii.es:20.500.12105/162982024-09-28T00:36:38Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19610

00925njm 22002777a 4500 dc Vorkamp, Katrin author Esteban-Lopez, Marta author Gilles, Liese author Göen, Thomas author Govarts, Eva author Hajeb, Parvaneh author Katsonouri, Andromachi author Knudsen, Lisbeth E author Kolossa-Gehring, Marike author Lindh, Christian author Nübler, Stefanie author Pedraza-Diaz, Susana author Santonen, Tiina author Castaño, Argelia author 2023-06 The European Human Biomonitoring Initiative (HBM4EU) ran from 2017 to 2022 with the aim of advancing and harmonizing human biomonitoring in Europe. More than 40,000 analyses were performed on human samples in different human biomonitoring studies in HBM4EU, addressing the chemical exposure of the general population, temporal developments, occupational exposure and a public health intervention on mercury in populations with high fish consumption. The analyses covered 15 priority groups of organic chemicals and metals and were carried out by a network of laboratories meeting the requirements of a comprehensive quality assurance and control system. The coordination of the chemical analyses included establishing contacts between sample owners and qualified laboratories and monitoring the progress of the chemical analyses during the analytical phase, also addressing status and consequences of Covid-19 measures. Other challenges were related to the novelty and complexity of HBM4EU, including administrative and financial matters and implementation of standardized procedures. Many individual contacts were necessary in the initial phase of HBM4EU. However, there is a potential to develop more streamlined and standardized communication and coordination in the analytical phase of a consolidated European HBM programme. Int J Hyg Environ Health. 2023 Jun;251:114183. 10.1016/j.ijheh.2023.114183 1618-131X International journal of hygiene and environmental health 37148759 http://hdl.handle.net/20.500.12105/16298 Aligned Studies Analytical phase Exposure Human biomonitoring (HBM) Laboratory network Quality assurance and control (QA/QC) Coordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU): Concepts, procedures and lessons learnt