2026-04-29T04:09:26Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/162542024-09-27T07:58:36Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Vicent, Lourdes
author
Álvarez-García, Jesús
author
Vazquez-Garcia, Rafael
author
González-Juanatey, José R
author
Rivera, Miguel
author
Segovia, Javier
author
Pascual-Figal, Domingo A
author
Bover, Ramón
author
Worner, Fernando
author
Fernández-Avilés, Francisco
author
Ariza-Sole, Albert
author
Martínez-Sellés, Manuel
funder
Instituto de Salud Carlos III
2023-07-17T08:25:31Z
2023-07-17T08:25:31Z
2023-04-21
J Clin Med. 2023 Apr 21;12(8):3028
2077-0383
http://hdl.handle.net/20.500.12105/16254
37109365
10.3390/jcm12083028
Journal of clinical medicine
Our aim was to determine the prognostic impact of coronary artery disease (CAD) on heart failure with reduced ejection fraction (HFrEF) mortality and readmissions. From a prospective multicenter registry that included 1831 patients hospitalized due to heart failure, 583 had a left ventricular ejection fraction of <40%. In total, 266 patients (45.6%) had coronary artery disease as main etiology and 137 (23.5%) had idiopathic dilated cardiomyopathy (DCM), and they are the focus of this study. Significant differences were found in Charlson index (CAD 4.4 ± 2.8, idiopathic DCM 2.9 ± 2.4, p < 0.001), and in the number of previous hospitalizations (1.1 ± 1, 0.8 ± 1.2, respectively, p = 0.015). One-year mortality was similar in the two groups: idiopathic DCM (hazard ratio [HR] = 1), CAD (HR 1.50; 95% CI 0.83-2.70, p = 0.182). Mortality/readmissions were also comparable: CAD (HR 0.96; 95% CI 0.64-1.41, p = 0.81). Patients with idiopathic DCM had a higher probability of receiving a heart transplant than those with CAD (HR 4.6; 95% CI 1.4-13.4, p = 0.012). The prognosis of HFrEF is similar in patients with CAD etiology and in those with idiopathic DCM. Patients with idiopathic DCM were more prone to receive heart transplant.
eng
Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction.
journal article
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Coronary Artery Disease J Clin Med 2023.pdf
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Coronary Artery Disease J Clin Med 2023.pdf.txt