2026-06-14T05:18:27Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/160692025-05-08T10:10:43Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16959
Repisalud
author
Petrova, Dafina
author
Garrido, Dunia
author
Špacírová, Zuzana
author
Fernández-Martínez, Nicolás Francisco
author
Ivanova, Ganka
author
Rodríguez-Barranco, Miguel
author
Pollan-Santamaria, Marina
author
Barrios-Rodríguez, Rocío
author
Sánchez, María José
funder
Asociación Española Contra el Cáncer
funder
Centro de Investigación Biomédica en Red - CIBERESP (Epidemiología y Salud Pública)
funder
Instituto de Salud Carlos III
funder
Ministerio de Ciencia (España)
funder
Agencia Estatal de Investigación (España)
funder
University of Granada (España)
2023-05-17T08:20:00Z
2023-05-17T08:20:00Z
2023-01
Psychooncology. 2023 Jan;32(1):13-24.
10.1002/pon.6064
1099-1611
Psycho-oncology
36345154
http://hdl.handle.net/20.500.12105/16069
Objective: Breast cancer survival is lower in low- and middle-income countries (LMICs) partially due to many women being diagnosed with late-stage disease. The patient interval refers to the time elapsed between the detection of symptoms and the first consultation with a healthcare provider and is considered one of the core indicators for early diagnosis and treatment. The goal of the current research was to conduct a meta-analysis of the duration of the patient interval in LMICs and investigate the socio-demographic and socio-cultural factors related to longer delays in presentation. Methods: We conducted a systematic review with meta-analysis (pre-registered protocol CRD42020200752). We searched seven information sources (2009-2022) and included 50 articles reporting the duration of patient intervals for 18,014 breast cancer patients residing in LMICs. Results: The longest patient intervals were reported in studies from the Middle East (3-4 months), followed by South-East Asia (2 months), Africa (1-2 months), Latin America (1 month), and Eastern Europe (1 month). Older age, not being married, lower socio-economic status, illiteracy, low knowledge about cancer, disregarding symptoms or not attributing them to cancer, fear, negative beliefs about cancer, and low social support were related to longer delays across most regions. Longer delays were also related to use of alternative medicine in the Middle East, South-East Asia, and Africa and distrust in the healthcare system in Eastern Europe. Conclusions: There is large variation in the duration of patient intervals across LMICs in different geographical regions. Patient intervals should be reduced and, for this purpose, it is important to explore their determinants taking into account the social, cultural, and economic context.
eng
Cancer
Early diagnosis
Help-seeking
Low- and middle-income countries
Oncology
Patient interval
Psycho-oncology
Psychosocial determinants
Duration of the patient interval in breast cancer and factors associated with longer delays in low-and middle-income countries: A systematic review with meta-analysis
research article
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application/pdf
DurationPatientIntervalBreastCancer_2023.pdf
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text/plain
DurationPatientIntervalBreastCancer_2023.pdf.txt