2026-07-21T14:36:59Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/160402025-04-08T09:30:51Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Asturias, Edwin J author Bai, Xilian author Bettinger, Julie A author Borrow, Ray author Castillo, Delia Nais author Caugant, Dominique A author Chacon, Grettel Chanto author Dinleyici, Ener Cagri author Echaniz-Aviles, Gabriela author García, Luis author Glennie, Linda author Harrison, Lee H author Howie, Rebecca L author Itsko, Mark author Lucidarme, Jay author Oliva Marin, Jose Eduardo author Marjuki, Henju author McNamara, Lucy A author Mustapha, Mustapha M author Robinson, Joan L author Romeu, Belkis author Sadarangani, Manish author Sáez-Llorens, Xavier author Sáfadi, Marco A P author Stephens, David S author Stuart, James M author Taha, Muhamed-Kheir author Tsang, Raymond S W author Vazquez-Moreno, Julio Alberto author De Wals, Philippe author 2022-12 This review summarizes the recent Global Meningococcal Initiative (GMI) regional meeting, which explored meningococcal disease in North America. Invasive meningococcal disease (IMD) cases are documented through both passive and active surveillance networks. IMD appears to be decreasing in many areas, such as the Dominican Republic (2016: 18 cases; 2021: 2 cases) and Panama (2008: 1 case/100,000; 2021: <0.1 cases/100,000); however, there is notable regional and temporal variation. Outbreaks persist in at-risk subpopulations, such as people experiencing homelessness in the US and migrants in Mexico. The recent emergence of β-lactamase-positive and ciprofloxacin-resistant meningococci in the US is a major concern. While vaccination practices vary across North America, vaccine uptake remains relatively high. Monovalent and multivalent conjugate vaccines (which many countries in North America primarily use) can provide herd protection. However, there is no evidence that group B vaccines reduce meningococcal carriage. The coronavirus pandemic illustrates that following public health crises, enhanced surveillance of disease epidemiology and catch-up vaccine schedules is key. Whole genome sequencing is a key epidemiological tool for identifying IMD strain emergence and the evaluation of vaccine strain coverage. The Global Roadmap on Defeating Meningitis by 2030 remains a focus of the GMI. J Infect. 2022 Dec;85(6):611-622. 10.1016/j.jinf.2022.10.022 1532-2742 The Journal of infection 36273639 http://hdl.handle.net/20.500.12105/16040 Antibiotic resistance Meningitis Meningococcal Neisseria species North America Vaccination Meningococcal disease in North America: Updates from the Global Meningococcal Initiative