2026-05-22T11:08:02Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/159452025-06-19T16:39:48Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19613
Repisalud
author
Global Burden of Disease 2019 Cancer Collaboration
author
Catalá-López, Ferrán
funder
Bill & Melinda Gates Foundation
funder
American Lebanese Syrian Associated Charities
funder
Alexander von Humboldt Foundation
funder
Federal Ministry of Education & Research (Alemania)
funder
NIH - National Cancer Institute (NCI) (Estados Unidos)
funder
Unión Europea. Comisión Europea. European Research Council (ERC)
funder
Unión Europea. Comisión Europea. H2020
funder
Novo Nordisk Foundation
funder
National Health and Medical Research Council (Australia)
funder
Ministry of Education, Science and Technological Development (Serbia)
funder
Medical Research Council (Reino Unido)
funder
Secretaría Nacional de Ciencia, Tecnología e Innovación (Panamá)
funder
King College London
funder
National Health Service (Reino Unido)
funder
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil)
funder
National Council for Scientific and Technological Development (Brasil)
funder
Cancer Prevention and Research Institute of Texas (Estados Unidos)
funder
National Health and Medical Research Council (Australia)
funder
Fundação para a Ciência e Tecnologia (Portugal)
funder
American Lebanese Syrian Associated Charities
funder
Kuwait University (Kuwait)
funder
National University of Malaysia (Malasia)
funder
NIH - National Cancer Institute (NCI) (Estados Unidos)
funder
Jazan University (Arabia Saudí)
funder
Romanian National Authority for Scientific Research and Innovation
funder
Ministry of Education (Brasil)
funder
National Heart Foundation of Australia
funder
NHS - Research Scotland (Reino Unido)
funder
Scottish Government (Reino Unido)
funder
Jatiya Kabi Kazi Nazrul Islam University (Bangladesh)
funder
Xiamen University Malaysia (Malasia)
funder
Manipal Academy of Higher Education (India)
funder
Sistema Nacional de Investigación (Panamá)
funder
Government of the Russian Federation
2023-05-03T11:21:45Z
2023-05-03T11:21:45Z
2022-03
JAMA Oncol. 2022 Mar 1;8(3):420-444.
10.1001/jamaoncol.2021.6987
2374-2445
JAMA oncology
34967848
http://hdl.handle.net/20.500.12105/15945
Importance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. Evidence review: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). Findings: In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. Conclusions and relevance: The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.
eng
Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019
research article
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URL
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File
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CancerIncidenceMortalityYears_2022.pdf
URL
https://repisalud.isciii.es/bitstreams/1051b9c5-6ad5-4a33-b9d4-76e14a1bad3b/download
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CancerIncidenceMortalityYears_2022.pdf.txt