2026-06-14T02:28:10Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/158752025-04-24T10:29:27Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16959col_20.500.12105_16962col_20.500.12105_16970col_20.500.12105_16974col_20.500.12105_16983col_20.500.12105_16990

00925njm 22002777a 4500 dc Turner, Michelle C author Gràcia-Lavedan, Esther author Papantoniou, Kyriaki author Aragones, Nuria author Castaño-Vinyals, Gemma author Dierssen-Sotos, Trinidad author Amiano, Pilar author Ardanaz, Eva author Marcos-Delgado, Alba author Molina-Barceló, Ana author Alguacil, Juan author Benavente, Yolanda author Belmonte, Thalia author Jimenez-Moleon, Jose J. author Marcos-Gragera, Rafael author Perez-Gomez, Beatriz author Gómez-Acebo, Inés author Pollan-Santamaria, Marina author Kogevinas, Manolis author 2022-12-16 Breast and prostate cancers have been associated with circadian disruption. Some previous studies examined associations of sleep duration and breast or prostate cancer risk though findings remain inconsistent. This study examines associations of a range of detailed sleep characteristics and breast and prostate cancer risk in a large-scale population-based case-control study, MCC-Spain. A total of 1738 incident breast cancer cases, 1112 prostate cancer cases and frequency matched controls (n = 1910, and 1493 respectively) were recruited. Detailed data on habitual sleep duration, quality, timing, and daytime napping ("siesta") were collected at recruitment. Additional data on sleep habits during both the previous year and at age 40 years were also subsequently captured. Adjusted odds ratios (ORs) and 95% confidence intervals (CI) were estimated. There were no associations of habitual sleep duration (h), timing of sleep, or any or specific sleep problems, and either breast and prostate cancer risk. There was a significant positive association of ever taking habitual siestas at recruitment and breast cancer risk (OR = 1.22, 95% CI 1.06-1.42), which strengthened with increased frequency or duration. There were also significant positive associations observed for both breast and prostate cancer, among those reporting recent sleep problems, but not sleep problems at age 40 years, in a subsequent circadian questionnaire. Adverse associations with siesta and disturbed sleep during the previous year likely reflect symptoms of developing/diagnosed cancer and comorbidities. Overall, there was no clear association between various sleep characteristics and breast or prostate cancer risk observed. Sci Rep. 2022 Dec 16;12(1):21807. 10.1038/s41598-022-25789-9 2045-2322 Scientific reports 36526666 http://hdl.handle.net/20.500.12105/15875 Sleep and breast and prostate cancer risk in the MCC-Spain study