2026-08-29T10:11:03Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/158512025-05-09T09:31:24Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16986

00925njm 22002777a 4500 dc Guerrero-Vadillo, María author Peñuelas, Marina author Domínguez, Angela author Godoy, Pere author Gomez-Barroso, Diana author Soldevila, Núria author Izquierdo, Conchita author Martínez, Ana author Torner, Núria author Avellón, Ana author Rius, Cristina author Varela Martinez, Maria del Carmen author 2022-12-14 The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016-2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space-time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15-44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space-time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging. Int J Environ Res Public Health. 2022 Dec 14;19(24):16775. 10.3390/ijerph192416775 1660-4601 International journal of environmental research and public health 36554666 http://hdl.handle.net/20.500.12105/15851 Hepatitis A virus Epidemiological surveillance MSM Outbreaks Space-time clustering Urban population Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak