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oai:repisalud.isciii.es:20.500.12105/157552024-09-27T08:30:22Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605

00925njm 22002777a 4500 dc Laveriano-Santos, Emily P author Arancibia-Riveros, Camila author Tresserra-Rimbau, Anna author Castro-Barquero, Sara author Ruiz-León, Ana María author Estruch, Ramón author Casas, Rosa author Bodega, Patricia author de Miguel, Mercedes author de Cos-Gandoy, Amaya author Martínez-Gómez, Jesús author Rodríguez, Carla author Santos-Beneit, Gloria author Fernández-Alvira, Juan M author Fernández-Jiménez, Rodrigo author Lamuela-Raventós, Rosa M author 2022 Cocoa-based products are a good source of flavonoids, which may have beneficial effects on metabolic health. The aim of this study is to assess the relationship between flavonoids from cocoa-based products and adiposity parameters in adolescents. A cross-sectional study was conducted involving 944 adolescents aged 11-14 years enrolled in the SI! Program for Secondary Schools trial in Spain with available baseline data from food frequency questionnaires and anthropometric measurements [weight, height, waist circumference (WC), and fat mass percentage (% FM) by bioimpedance analysis]. Fat mass index (FMI) and waist-to-height ratio (WHtR) were obtained by dividing fat mass by height and WC by height, respectively. Body mass index (BMI), WC, and FMI for age and gender z-score were calculated. Overweight/obesity was defined as BMI ≥ 85th percentile and excess adiposity as %FM or FMI ≥ 75th percentile. WC ≥ 90th percentile and WHtR with a 0.5 threshold were considered as criteria of abdominal obesity. Multilevel mixed-effect regressions were used to evaluate the association between flavonoids from cocoa-based products and adiposity parameters. Municipalities and schools were considered random effects. Participants with a higher flavonoid intake from cocoa-based products had lower WC z-score [B = -0.04, 95% CI (-0.07; -0.01), P-for trend = 0.045] and WHtR [B = -0.01, 95% CI (-0.02; -0.01), P- for trend < 0.001]. They also had lower probability of having abdominal obesity [OR 0.66, 95% CI (0.52; 0.85), P- for trend = 0.001]. Inverse associations were observed between flavonoids from cocoa powder and BMI z-score [B = -0.08, 95% CI (-0.12; -0.05), P < 0.001], WC z-score [B = -0.06, 95% CI (-0.11; -0.02), P = 0.003], WHtR [B = -0.01, 95% CI (-0.01; -0.00), P < 0.001], %FM [B = -1.11, 95% CI (-1.48; -0.75), P < 0.001], and FMI z-score [B = -0.18, 95% CI (-0.20; -0.17), P < 0.001]. Regarding dark chocolate, an inverse association only with WC z-score [B = -0.06, 95% CI (-0.08; -0.05), P < 0.001] was found. However, no association was observed between flavonoids from milk chocolate intake and anthropometric parameters. A higher intake of flavonoids from cocoa-based products was associated with lower adiposity parameters and a lower probability of presenting abdominal obesity. Front Nutr. 2022 Jul 6;9:931171 2296-861X http://hdl.handle.net/20.500.12105/15755 35873437 10.3389/fnut.2022.931171 Frontiers in nutrition Flavonoid Intake From Cocoa-Based Products and Adiposity Parameters in Adolescents in Spain.