2026-04-29T04:10:14Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/156982024-09-27T10:01:04Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Llorente, Vicente
author
Velarde, Pedro
author
Desco, Manuel
author
Gómez-Gaviro, María Victoria
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Instituto de Salud Carlos III
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Comunidad de Madrid (España)
funder
Fundación ProCNIC
funder
Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España)
2023-03-23T10:48:06Z
2023-03-23T10:48:06Z
2022-09-26
Cells. 2022 Sep 26;11(19):3002
http://hdl.handle.net/20.500.12105/15698
36230964
10.3390/cells11193002
2073-4409
Cells
Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all components of the central nervous system (CNS) during embryogenesis, but also activate in response to injury and disease and maintain a certain level of neurogenic activity throughout adulthood. This activity takes place in specialized regions of the brain, the neurovascular niches, whose main role is to control the behaviour of the CNS. In adult mammals, two main "canonical" niches have been described: The subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus. This review discusses our current understanding of the neural stem cells and their canonical niches, as well as their structure, behaviours, and role in neural disease.
eng
Current Understanding of the Neural Stem Cell Niches.
review
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URL
https://repisalud.isciii.es/bitstreams/5c1b5299-d683-4723-b7d0-d610ea1dc6f3/download
File
MD5
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application/pdf
Current Understanding of the Neural Stem Cells 2022.pdf
URL
https://repisalud.isciii.es/bitstreams/ec14995e-1312-4732-a7b9-cb51b76151a2/download
File
MD5
bc6e7f02936902636983ce57615e6e20
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text/plain
Current Understanding of the Neural Stem Cells 2022.pdf.txt