2026-04-27T01:59:27Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/156962024-09-27T08:35:58Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Sánchez-Álvarez, Miguel
author
del Pozo, Miguel Angel
author
Bosch, Marta
author
Pol, Albert
funder
Comunidad de Madrid (España)
funder
Ministerio de Ciencia e Innovación (España)
funder
European Molecular Biology Organization
funder
Fundación La Caixa
funder
Fundación La Marató TV3
funder
Instituto de Salud Carlos III
funder
Fundación ProCNIC
funder
Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España)
funder
Asociación Española Contra el Cáncer
2023-03-23T09:47:59Z
2023-03-23T09:47:59Z
2022
Front Cell Dev Biol. 2022 Jun 8;10:901321
2296-634X
http://hdl.handle.net/20.500.12105/15696
35756995
10.3389/fcell.2022.901321
Frontiers in cell and developmental biology
Lipid droplets (LDs) are spherical, single sheet phospholipid-bound organelles that store neutral lipids in all eukaryotes and some prokaryotes. Initially conceived as relatively inert depots for energy and lipid precursors, these highly dynamic structures play active roles in homeostatic functions beyond metabolism, such as proteostasis and protein turnover, innate immunity and defense. A major share of the knowledge behind this paradigm shift has been enabled by the use of systematic molecular profiling approaches, capable of revealing and describing these non-intuitive systems-level relationships. Here, we discuss these advances and some of the challenges they entail, and highlight standing questions in the field.
eng
Insights Into the Biogenesis and Emerging Functions of Lipid Droplets From Unbiased Molecular Profiling Approaches.
review
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URL
https://repisalud.isciii.es/bitstreams/16ce2664-ed73-4bf8-af1a-9a8929912881/download
File
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Insights Into the Biogenesis Front Cell Dev Biol 2022.pdf
URL
https://repisalud.isciii.es/bitstreams/1f578e45-1f7a-43e6-ad69-da596ee8c945/download
File
MD5
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Insights Into the Biogenesis Front Cell Dev Biol 2022.pdf.txt