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oai:repisalud.isciii.es:20.500.12105/156922024-09-27T09:54:17Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605

00925njm 22002777a 4500 dc Peñaloza-Martínez, Eduardo author Moreno, Guillermo author Aroca-Crevillen, Alejandra author Huertas, Sergio author Vicent, Lourdes author Rosillo, Nicolás author Hidalgo, Andres author Bueno, Hector author 2022-02-11 Biological circadian rhythms in living organisms are regulated by molecular clocks. Several of these clocks are present in blood vessels, peripheral tissues, and immune cells. There is strong evidence linking dysregulation of circadian rhythms to the development of cardiovascular disease. Dysregulation of circadian rhythms is believed to activate inflammatory processes at specific times of day, leading to an increased risk of thrombosis and atherosclerosis progression. Research into circadian clock genes and molecular networks has the potential to identify therapeutic targets to reduce cardiovascular risk. In this review, we summarize the evidence linking circadian rhythms to thrombosis and atherothrombotic events and discuss potential therapeutic implications. Front Biosci (Landmark Ed). 2022 Feb 11;27(2):51 10.31083/j.fbl2702051 2768-6698 Frontiers in bioscience (Landmark edition) 35226994 http://hdl.handle.net/20.500.12105/15692 Circadian rhythms in thrombosis and atherothrombotic events.