2026-04-29T12:23:06Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/156722024-09-27T10:03:14Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Laveriano-Santos, Emily P
author
Arancibia-Riveros, Camila
author
Parilli-Moser, Isabella
author
Ramírez-Garza, Sonia L
author
Tresserra-Rimbau, Anna
author
Ruiz-León, Ana María
author
Estruch, Ramón
author
Bodega, Patricia
author
de Miguel, Mercedes
author
de Cos-Gandoy, Amaya
author
Carral, Vanesa
author
Santos-Beneit, Gloria
author
Fernández-Alvira, Juan M
author
Fernández-Jiménez, Rodrigo
author
Lamuela-Raventós, Rosa M
funder
Fundación La Caixa
funder
Fundación La Marató TV3
funder
Ministerio de Ciencia e Innovación (España)
funder
Instituto de Salud Carlos III
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Fundación ProCNIC
funder
Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España)
2023-03-17T12:52:50Z
2023-03-17T12:52:50Z
2022-09-14
Sci Rep. 2022 Sep 14;12(1):15468
10.1038/s41598-022-19684-6
2045-2322
Scientific reports
36104478
http://hdl.handle.net/20.500.12105/15672
To study the relationship between urinary total polyphenol excretion (TPE) in adolescents and ideal cardiovascular (CVH) metrics. 1151 adolescents aged 12.04 (0.46) years participating in the SI! Program for Secondary Schools were selected based on the availability of urine samples and information required to assess CVH metrics. Data on health behaviours (smoking status, body mass index, physical activity, and healthy diet) and health factors (blood pressure, total cholesterol, and blood glucose) were used to calculate the CVH metrics. TPE in urine was analysed by a Folin-Ciocalteu method after solid-phase extraction. Associations between TPE (categorized into tertiles) and CVH metrics (total and separate scores) were assessed using multilevel mixed-effect regression models. Higher TPE levels were associated with higher (healthier) CVH scores and ideal smoking status (OR 1.54, 95% CI 1.10; 1.87, p value = 0.007), physical activity (OR 1.12, 95% CI 1.02; 1.23, p value = 0.022) and total cholesterol (OR 1.78, 95% CI 1.16; 2.73, p value = 0.009) after multivariate adjustment. An association between TPE and total CVH scores was observed only in boys. Girls with higher TPE had higher rates of ideal total cholesterol and blood pressure. According to our findings, higher urinary TPE is related to better CVH scores, with relevant differences in this association by gender.
eng
Total urinary polyphenols and ideal cardiovascular health metrics in Spanish adolescents enrolled in the SI Program: a cross-sectional study.
journal article
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Total urinary polyphenols Sci Rep 2022.pdf
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1184082
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Total urinary polyphenols Sci Rep 2022.pdf
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https://repisalud.isciii.es/bitstreams/82a7b9d6-6765-4677-a70f-ab7de41a1d97/download
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Total urinary polyphenols Sci Rep 2022.pdf.txt