2026-05-17T00:15:31Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/156642024-09-27T08:39:10Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Cómitre-Mariano, Blanca
author
Martínez-García, Magdalena
author
García-Gálvez, Bárbara
author
Paternina-Die, María
author
Desco, Manuel
author
Carmona, Susanna
author
Gómez-Gaviro, María Victoria
funder
Ministerio de Ciencia e Innovación (España)
funder
Instituto de Salud Carlos III
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
US-UK Fulbright Commission
funder
Comunidad de Madrid (España)
funder
Fundación La Caixa
funder
Unión Europea. Comisión Europea. European Research Council (ERC)
funder
Unión Europea. Comisión Europea. Horizonte Europa
funder
Fundación ProCNIC
funder
Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España)
2023-03-17T10:46:30Z
2023-03-17T10:46:30Z
2022-01-21
iScience. 2021 Dec 29;25(1):103664
10.1016/j.isci.2021.103664
2589-0042
iScience
35072002
http://hdl.handle.net/20.500.12105/15664
There is a bidirectional transplacental cell trafficking between mother and fetus during pregnancy in placental mammals. The presence and persistence of fetal cells in maternal tissues are known as fetal microchimerism (FMc). FMc has high multilineage potential with a great ability to differentiate and functionally integrate into maternal tissue. FMc has been found in various maternal tissues in animal models and humans. Its permanence in the maternal body up to decades after delivery suggests it might play an essential role in maternal pathophysiology. Studying the presence, localization, and characteristics of FMc in maternal tissues is key to understanding its impact on the woman's body. Here we comprehensively review the existence of FMc in different species and organs and tissues, aiming to better characterize their possible role in human health and disease. We also highlight several methodological considerations that would optimize the detection, quantification, and functional determination of FMc.
eng
Feto-maternal microchimerism: Memories from pregnancy.
review
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URL
https://repisalud.isciii.es/bitstreams/6cf56a72-1ee4-4c89-ab52-9bacba294b99/download
File
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Feto_maternalmicrochimerism_ iScience 2021.pdf
URL
https://repisalud.isciii.es/bitstreams/9ed1f0e3-8850-4fec-b7ad-f0b382c2a4f8/download
File
MD5
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text/plain
Feto_maternalmicrochimerism_ iScience 2021.pdf.txt