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00925njm 22002777a 4500 dc Castelpietra, Giulio author Skrindo Knudsen, Ann Kristin author Agardh, Emilie E author Armocida, Benedetta author Beghi, Massimiliano author Moesgaard Iburg, Kim author Logroscino, Giancarlo author Ma, Rui author Starace, Fabrizio author Steel, Nicholas author Addolorato, Giovanni author Andrei, Catalina Liliana author Andrei, Tudorel author Ayuso-Mateos, José Luis author Banach, Maciej author Bärnighausen, Till Winfried author Barone-Adesi, Francesco author Srikanth Bhagavathula, Akshaya author Carvalho, Félix author Carvalho, Márcia author Singh Chandan, Joht author Kumar Chattu, Vijay author Couto, Rosa A S author Cruz-Martins, Natália author Dargan, Paul I author Deuba, Keshab author Dias-da-Silva, Diana author Fagbamigbe, Adeniyi Francis author Fernandes, Eduarda author Ferrara, Pietro author Fischer, Florian author Andras Gaal, Peter author Gialluisi, Alessandro author Haagsma, Juanita A author Haro, Josep Maria author Hasan, M Tasdik author Hasan, Syed Shahzad author Hostiuc, Sorin author Iacoviello, Licia author Iavicoli, Ivo author Jamshidi, Elham author Jonas, Jost B author Joo, Tamas author Jozwiak, Jacek Jerzy author Katikireddi, Srinivasa Vittal author Kauppila, Joonas H author Khan, Moien A B author Kisa, Adnan author Kisa, Sezer author Kivimäki, Mika author Koly, Kamrun Nahar author Koyanagi, Ai author Kumar, Manasi author Lallukka, Tea author Langguth, Berthold author Ledda, Caterina author Lee, Paul H author Lega, Ilaria author Linehan, Christine author Loureiro, Joana A author Madureira-Carvalho, Áurea M author Martinez-Raga, Jose author Mathur, Manu Raj author McGrath, John J author Mechili, Enkeleint A author Mentis, Alexios-Fotios A author Mestrovic, Tomislav author Miazgowski, Bartosz author Mirica, Andreea author Mirijello, Antonio author Moazen, Babak author Mohammed, Shafiu author Mulita, Francesk author Nagel, Gabriele author Negoi, Ionut author Negoi, Ruxandra Irina author Ebuka Nwatah, Vincent author Padron-Monedero, Alicia author Panda-Jonas, Songhomitra author Pardhan, Shahina author Pasovic, Maja author Patel, Jay author Petcu, Ionela-Roxana author Pinheiro, Marina author Pollok, Richard Charles G author Postma, Maarten J author Laith Rawaf, David author Rawaf, Salman author Romero-Rodríguez, Esperanza author Ronfani, Luca author Sagoe, Dominic author Sanmarchi, Francesco author Schaub, Michael P author Tadesse Sharew, Nigussie author Shiri, Rahman author Shokraneh, Farhad author Sigfusdottir, Inga Dora author Silva, João Pedro author Silva, Renata author Socea, Bogdan author Szócska, Miklós author Tabarés-Seisdedos, Rafael author Torrado, Marco author Tovani-Palone, Marcos Roberto author Vasankari, Tommi Juhani author Veroux, Massimiliano author Viner, Russell M author Werdecker, Andrea author Winkler, Andrea Sylvia author Hay, Simon I author Ferrari, Alize J author Naghavi, Mohsen author Allebeck, Peter author Monasta, Lorenzo author 2022-04-01 Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time. Methods: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated. Findings: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 - 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432-912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9-412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (-29·1%;23·8-38·5). YLLs decreased in self-harm (-27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs. Interpretation: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. Lancet Reg Health Eur 2022 Apr 1;16:100341. 10.1016/j.lanepe.2022.100341 2666-7762 The Lancet regional health. Europe 35392452 http://hdl.handle.net/20.500.12105/15547 Young people Mental health Mental disorders Self-harm Substance use Europe The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019