2026-06-14T05:18:52Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/154912025-03-26T11:32:40Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608col_20.500.12105_19609
Repisalud
author
Melidou, Angeliki
author
Broberg, Eeva K
author
European region influenza surveillance network
author
Pozo Sanchez, Francisco
author
Casas Flecha, Inmaculada
author
Larrauri, Amparo
author
Oliva Dominguez, Jesus Angel
author
Delgado-Sanz, Concepcion
2023-02-10T11:58:52Z
2023-02-10T11:58:52Z
2017-09-05
Vaccine. 2017 Sep 5;35(37):4828-4835.
10.1016/j.vaccine.2017.07.057
1873-2518
Vaccine
28780977
http://hdl.handle.net/20.500.12105/15491
During the European 2016/17 influenza season, A(H3N2) viruses have predominated and the majority clustered in genetic subclade 3C.2a1. Genetic analyses showed that circulating viruses have undergone considerable genetic diversification of the haemagglutinin gene from the current vaccine virus A/Hong Kong/4801/2014 (clade 3C.2a), but the antigenic data that is limited by the challenges with the antigenic characterisation of currently circulating A(H3N2) viruses, showed no clear evidence of antigenic change. The recommended A(H3N2) vaccine component for the northern hemisphere 2017/18 influenza season remained unchanged. However, early and mid-season vaccine effectiveness (VE) estimates were suggestive of reduced VE against A(H3N2) viruses.
eng
A(H3N2)
Amino acid substitution
Emergence
Europe
Influenza virus
Season
Surveillance
Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European Region to the WHO vaccine composition consultation for northern hemisphere 2017/18
research article
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PredominanceInfluenzaA_H3N2_Virus_2017.pdf.txt
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