2026-04-29T07:25:13Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/152372025-05-08T12:31:45Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19612col_20.500.12105_16988

00925njm 22002777a 4500 dc Sarria-Santamera, Antonio author Khamitova, Zaukiya author Gusmanov, Arnur author Terzic, Milan author Polo de Santos, Maria del Mar author Ortega, Miguel A author Asúnsolo-Del-Barco, Ángel author 2022-08-20 Background: Endometriosis is a complex gynecologic disorder that has been associated with a higher risk of ovarian cancer. The purpose of this work is to determine to what extent a history of endometriosis is a risk factor for ovarian cancer in a Spanish population. Methods: A retrospective case-control study was conducted using de-identified data from the Spanish National Health System's "Primary Care Clinical Database" and "Hospital Minimum Basic Data Set" for the period 2013-2017. Multiple logistics regression analysis was conducted to determine associations between ovarian cancer and endometriosis controlled by sociodemographic characteristics and comorbidities. Results: Data from 608,980 women were analyzed, with 4505 presenting ovarian cancer. Endometriosis patients were shown to have a 2.66-fold increased risk of ovarian cancer when compared to those who did not have endometriosis by controlling age and other relevant comorbidities. Conclusions: This case-control study based on clinical administrative data has found that a history of endometriosis is independently associated with an increased risk of ovarian cancer. More research is needed to determine if a history of endometriosis affects survival results in ovarian cancer patients. J Pers Med. 2022 Aug 20;12(8):1337. 2075-4426 http://hdl.handle.net/20.500.12105/15237 36013285 10.3390/jpm12081337 Journal of Personalized Medicine Ovarian cancer Risk Sociodemographic characteristics Endometriosis History of Endometriosis Is Independently Associated with an Increased Risk of Ovarian Cancer