2026-06-30T03:57:10Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/149942024-11-29T12:04:20Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16987

00925njm 22002777a 4500 dc Giacobbe, Daniele R author Cortegiani, Andrea author Karaiskos, Ilias author Mercier, Toine author Tejada, Sofia author Peghin, Maddalena author Grecchi, Cecilia author Rebuffi, Chiara author Asperges, Erika author Zuccaro, Valentina author Scudeller, Luigia author Bassetti, Matteo author FUNDICU investigators author Alastruey-Izquierdo, Ana author 2021-02-28 The Fungal Infections Definitions in Intensive Care Unit (ICU) patients (FUNDICU) project aims to provide standard sets of definitions for invasive fungal diseases (IFDs) in critically ill, adult patients, including invasive aspergillosis (IA), invasive candidiasis (IC), Pneumocystis jirovecii pneumonia (PJP), and other non-IA, non-IC IFDs. The first step of the project was the conduction of separated systematic reviews of the characteristics and applicability to critically ill, adult patients outside classical populations at risk (hematology patients, solid organ transplant recipients) of available definitions and diagnostic tests for IFDs. We report here the results of two systematic reviews exploring the performance of available definitions and tests, for PJP and for other non-IA, non-IC IFDs. Starting from 2585 and 4584 records for PJP and other IFDs, respectively, 89 and 61 studies were deemed as eligible for full-text evaluation. However, only two studies for PJP and no studies for other IFDs met the FUNDICU protocol criteria for inclusion in qualitative synthesis. Currently, there is no sufficient solid data for directly evaluating the performance of existing definitions and laboratory tests for the diagnosis of PJP and other non-IA, non-IC IFDs in critically ill adult patients outside classical populations at risk. J Fungi (Basel). 2021 Feb 28;7(3):176. 10.3390/jof7030176 2309-608X Journal of fungi (Basel, Switzerland) 33670864 http://hdl.handle.net/20.500.12105/14994 Pneumocystis PJP Diagnosis Biomarker IFD Invasive fungal diseases Performance of Existing Definitions and Tests for the Diagnosis of Invasive Fungal Diseases other than Invasive Candidiasis and Invasive Aspergillosis in Critically Ill, Adult Patients: A Systematic Review with Qualitative Evidence Synthesis