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oai:repisalud.isciii.es:20.500.12105/147682025-03-27T10:32:52Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19613

00925njm 22002777a 4500 dc Cromwell, Elizabeth A author Osborne, Joshua C P author Unnasch, Thomas R author Basáñez, Maria-Gloria author Gass, Katherine M author Barbre, Kira A author Hill, Elex author Johnson, Kimberly B author Donkers, Katie M author Shirude, Shreya author Schmidt, Chris A author Adekanmbi, Victor author Adetokunboh, Olatunji O author Afarideh, Mohsen author Ahmadpour, Ehsan author Ahmed, Muktar Beshir author Akalu, Temesgen Yihunie author Al-Aly, Ziyad author Alanezi, Fahad Mashhour author Alanzi, Turki M author Alipour, Vahid author Andrei, Catalina Liliana author Ansari, Fereshteh author Ansha, Mustafa Geleto author Anvari, Davood author Appiah, Seth Christopher Yaw author Arabloo, Jalal author Arnold, Benjamin F author Ausloos, Marcel author Ayanore, Martin Amogre author Baig, Atif Amin author Banach, Maciej author Barac, Aleksandra author Bärnighausen, Till Winfried author Bayati, Mohsen author Bhattacharyya, Krittika author Bhutta, Zulfiqar A author Bibi, Sadia author Bijani, Ali author Bohlouli, Somayeh author Bohluli, Mahdi author Brady, Oliver J author Bragazzi, Nicola Luigi author Butt, Zahid A author Carvalho, Félix author Chatterjee, Souranshu author Chattu, Vijay Kumar author Chattu, Soosanna Kumary author Cormier, Natalie Maria author Dahlawi, Saad M A author Damiani, Giovanni author Daoud, Farah author Darwesh, Aso Mohammad author Daryani, Ahmad author Deribe, Kebede author Dharmaratne, Samath Dhamminda author Diaz, Daniel author Do, Hoa Thi author El Sayed Zaki, Maysaa author El Tantawi, Maha author Elemineh, Demelash Abewa author Faraj, Anwar author Fasihi Harandi, Majid author Fatahi, Yousef author Feigin, Valery L author Fernandes, Eduarda author Foigt, Nataliya A author Foroutan, Masoud author Franklin, Richard Charles author Gubari, Mohammed Ibrahim Mohialdeen author Guido, Davide author Guo, Yuming author Haj-Mirzaian, Arvin author Hamagharib Abdullah, Kanaan author Hamidi, Samer author Herteliu, Claudiu author Hidru, Hagos Degefa de author Higazi, Tarig B author Hossain, Naznin author Hosseinzadeh, Mehdi author Househ, Mowafa author Ilesanmi, Olayinka Stephen author Ilic, Milena D author Ilic, Irena M author Iqbal, Usman author Irvani, Seyed Sina Naghibi author Jha, Ravi Prakash author Joukar, Farahnaz author Jozwiak, Jacek Jerzy author Kabir, Zubair author Kalankesh, Leila R author Kalhor, Rohollah author Karami Matin, Behzad author Karimi, Salah Eddin author Kasaeian, Amir author Kavetskyy, Taras author Kayode, Gbenga A author Kazemi Karyani, Ali author Kelbore, Abraham Getachew author Keramati, Maryam author Khalilov, Rovshan author Khan, Ejaz Ahmad author Khan, Md Nuruzzaman Nuruzzaman author Khatab, Khaled author Khater, Mona M author Kianipour, Neda author Kibret, Kelemu Tilahun author Kim, Yun Jin author Kosen, Soewarta author Krohn, Kris J author Kusuma, Dian author La Vecchia, Carlo author Lansingh, Van Charles author Lee, Paul H author LeGrand, Kate E author Li, Shanshan author Longbottom, Joshua author Magdy Abd El Razek, Hassan author Magdy Abd El Razek, Muhammed author Maleki, Afshin author Mamun, Abdullah A author Manafi, Ali author Manafi, Navid author Mansournia, Mohammad Ali author Martins-Melo, Francisco Rogerlândio author Mazidi, Mohsen author McAlinden, Colm author Meharie, Birhanu Geta author Mendoza, Walter author Mengesha, Endalkachew Worku author Mengistu, Desalegn Tadese author Mereta, Seid Tiku author Mestrovic, Tomislav author Miller, Ted R author Miri, Mohammad author Moghadaszadeh, Masoud author Mohammadian-Hafshejani, Abdollah author Mohammadpourhodki, Reza author Mohammed, Shafiu author Mohammed, Salahuddin author Moradi, Masoud author Moradzadeh, Rahmatollah author Moraga, Paula author Mosser, Jonathan F author Naderi, Mehdi author Nagarajan, Ahamarshan Jayaraman author Naik, Gurudatta author Negoi, Ionut author Nguyen, Cuong Tat author Nguyen, Huong Lan Thi author Nguyen, Trang Huyen author Nikbakhsh, Rajan author Oancea, Bogdan author Olagunju, Tinuke O author Olagunju, Andrew T author Omar Bali, Ahmed author Onwujekwe, Obinna E author Pana, Adrian author Pourjafar, Hadi author Rahim, Fakher author Rahman, Mohammad Hifz Ur author Rathi, Priya author Rawaf, Salman author Rawaf, David Laith author Rawassizadeh, Reza author Resnikoff, Serge author Reta, Melese Abate author Rezapour, Aziz author Rubagotti, Enrico author Rubino, Salvatore author Sadeghi, Ehsan author Saghafipour, Abedin author Sajadi, S Mohammad author Samy, Abdallah M author Sarmiento Suárez, Rodrigo author Sawhney, Monika author Schipp, Megan F author Shaheen, Amira A author Shaikh, Masood Ali author Shamsizadeh, Morteza author Sharafi, Kiomars author Sheikh, Aziz author Shetty, B Suresh Kumar author Shin, Jae Il author Shivakumar, K M author Simonetti, Biagio author Singh, Jasvinder A author Skiadaresi, Eirini author Soheili, Amin author Soltani, Shahin author Spurlock, Emma Elizabeth author Sufiyan, Mu'awiyyah Babale author Tabuchi, Takahiro author Tapak, Leili author Thompson, Robert L author Thomson, Alan J author Traini, Eugenio author Tran, Bach Xuan author Ullah, Irfan author Ullah, Saif author Uneke, Chigozie Jesse author Unnikrishnan, Bhaskaran author Uthman, Olalekan A author Vinkeles Melchers, Natalie V S author Violante, Francesco S author Wolde, Haileab Fekadu author Wonde, Tewodros Eshete author Yamada, Tomohide author Yaya, Sanni author Yazdi-Feyzabadi, Vahid author Yip, Paul author Yonemoto, Naohiro author Yousof, Hebat-Allah Salah A author Yu, Chuanhua author Yu, Yong author Yusefzadeh, Hasan author Zaki, Leila author Zaman, Sojib Bin author Zamanian, Maryam author Zhang, Zhi-Jiang author Zhang, Yunquan author Ziapour, Arash author Hay, Simon I author Pigott, David M author 2021-07-28 Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitability concordant with locations where onchocerciasis has been previously detected. This threshold value was then used to classify IUs (more suitable or less suitable) based on the location within the IU with the largest mean prediction. Mean estimates of environmental suitability suggest large areas across West and Central Africa, as well as focal areas of East Africa, are suitable for onchocerciasis transmission, consistent with the presence of current control and elimination of transmission efforts. The ROC analysis identified a mean environmental suitability index of 0·71 as a threshold to classify based on the location with the largest mean prediction within the IU. Of the IUs considered for mapping surveys, 50·2% exceed this threshold for suitability in at least one 5 × 5-km location. The formidable scale of data collection required to map onchocerciasis endemicity across the African continent presents an opportunity to use spatial data to identify areas likely to be suitable for onchocerciasis transmission. National onchocerciasis elimination programmes may wish to consider prioritising these IUs for mapping surveys as human resources, laboratory capacity, and programmatic schedules may constrain survey implementation, and possibly delaying MDA initiation in areas that would ultimately qualify. PLoS Negl Trop Dis. 2021 Jul 28;15(7):e0008824. 10.1371/journal.pntd.0008824 1935-2735 PLoS Neglected Tropical Diseases 34319976 http://hdl.handle.net/20.500.12105/14768 Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning