2026-08-05T11:42:18Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/147542025-03-21T10:59:24Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Köster, Pamela Carolina
author
Renelies-Hamilton, Justinn
author
Dotras, Laia
author
Llana, Manuel
author
Vinagre-Izquierdo, Celia
author
Prakas, Petras
author
Sneideris, Donatas
author
Dashti, Alejandro
author
Bailo-Barroso, Begoña
author
Lanza-Suarez, Marta
author
Jiménez-Mejías, Alejandra
author
Muñoz García, Carlota
author
Muadica, Aly Salimo
author
Gonzalez-Barrio, David
author
Rubio Muñoz, Jose Miguel
author
Fuentes Corripio, Isabel
author
Ponce-Gordo, Francisco
author
Calero-Bernal, Rafael
author
Carmena, David
funder
Ministerio de Economía y Competitividad (España)
funder
Instituto de Salud Carlos III
2022-07-20T11:30:20Z
2022-07-20T11:30:20Z
2021-11-17
Animals (Basel). 2021 Nov 17;11(11):3291.
10.3390/ani11113291
2076-2615
Animals (Basel)
34828022
http://hdl.handle.net/20.500.12105/14754
Wild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal and blood protists as well as filariae in faecal samples (n = 234) from wild chimpanzees in the Dindefelo Community Nature Reserve, Senegal. PCR-based results revealed the presence of intestinal potential pathogens (Sarcocystis spp.: 11.5%; Giardia duodenalis: 2.1%; Cryptosporidium hominis: 0.9%), protist of uncertain pathogenicity (Blastocystis sp.: 5.6%), and commensal species (Entamoeba dispar: 18.4%; Troglodytella abrassarti: 5.6%). Entamoeba histolytica, Enterocytozoon bieneusi, and Balantioides coli were undetected. Blood protists including Plasmodium malariae (0.4%), Trypanosoma brucei (1.3%), and Mansonella perstans (9.8%) were also identified. Sanger sequencing analyses revealed host-adapted genetic variants within Blastocystis, but other parasitic pathogens (C. hominis, P. malariae, T. brucei, M. perstans) have zoonotic potential, suggesting that cross-species transmission between wild chimpanzees and humans is possible in areas where both species overlap. Additionally, we explored potential interactions between intestinal/blood protist species and seasonality and climate variables. Chimpanzees seem to play a more complex role on the epidemiology of pathogenic and commensal protist and nematode species than initially anticipated.
eng
PCR
Epidemiology
Non-human primates
Protists
Seasonality
Zoonoses
Conservation
Endangered
Genotyping
Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegal
research article
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