2026-08-05T11:42:12Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/147542025-03-21T10:59:24Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Köster, Pamela Carolina author Renelies-Hamilton, Justinn author Dotras, Laia author Llana, Manuel author Vinagre-Izquierdo, Celia author Prakas, Petras author Sneideris, Donatas author Dashti, Alejandro author Bailo-Barroso, Begoña author Lanza-Suarez, Marta author Jiménez-Mejías, Alejandra author Muñoz García, Carlota author Muadica, Aly Salimo author Gonzalez-Barrio, David author Rubio Muñoz, Jose Miguel author Fuentes Corripio, Isabel author Ponce-Gordo, Francisco author Calero-Bernal, Rafael author Carmena, David author 2021-11-17 Wild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal and blood protists as well as filariae in faecal samples (n = 234) from wild chimpanzees in the Dindefelo Community Nature Reserve, Senegal. PCR-based results revealed the presence of intestinal potential pathogens (Sarcocystis spp.: 11.5%; Giardia duodenalis: 2.1%; Cryptosporidium hominis: 0.9%), protist of uncertain pathogenicity (Blastocystis sp.: 5.6%), and commensal species (Entamoeba dispar: 18.4%; Troglodytella abrassarti: 5.6%). Entamoeba histolytica, Enterocytozoon bieneusi, and Balantioides coli were undetected. Blood protists including Plasmodium malariae (0.4%), Trypanosoma brucei (1.3%), and Mansonella perstans (9.8%) were also identified. Sanger sequencing analyses revealed host-adapted genetic variants within Blastocystis, but other parasitic pathogens (C. hominis, P. malariae, T. brucei, M. perstans) have zoonotic potential, suggesting that cross-species transmission between wild chimpanzees and humans is possible in areas where both species overlap. Additionally, we explored potential interactions between intestinal/blood protist species and seasonality and climate variables. Chimpanzees seem to play a more complex role on the epidemiology of pathogenic and commensal protist and nematode species than initially anticipated. Animals (Basel). 2021 Nov 17;11(11):3291. 10.3390/ani11113291 2076-2615 Animals (Basel) 34828022 http://hdl.handle.net/20.500.12105/14754 PCR Epidemiology Non-human primates Protists Seasonality Zoonoses Conservation Endangered Genotyping Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegal