2026-06-14T03:36:04Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/145132025-05-08T08:36:50Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608
Repisalud
author
Martínez-Martín, Pablo
author
Rojo-Abuin, Jose Manuel
author
Rizos, Alexandra
author
Rodriguez-Blazquez, Carmen
author
Trenkwalder, Claudia
author
Perkins, Lauren
author
Sauerbier, Anna
author
Odin, Per
author
Antonini, Angelo
author
Chaudhuri, Kallol Ray
author
International Parkinson's Disease Non-Motor Group (PDNMG)
author
EUROPAR Study Group
author
King's Parkinson's Disease Pain Scale (KPPS)
funder
Parkinsons UK
funder
National Institute for Health Research (Reino Unido)
funder
NIHR - Mental Health Biomedical Research Centre (Reino Unido)
funder
South London and Maudsley NHS Foundation Trust (Reino Unido)
funder
Imperial College London (Reino Unido)
2022-05-25T09:00:05Z
2022-05-25T09:00:05Z
2017-03-15
NPJ Parkinsons Dis. 2017 Mar 15;3:8.
10.1038/s41531-017-0009-1
2373-8057
NPJ Parkinson's Disease
28649608
http://hdl.handle.net/20.500.12105/14513
In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom. The regular scores were used for the other analyses. Health-related quality of lifewas evaluated with EQ-5D-3L and PDQ-8 questionnaires. Parkinson's disease patients experienced more pain modalities than controls. In patients, Pain around joints (King's Parkinson's disease pain scale item 1) and Pain while turning in bed (item 8) were the most prevalent types of pain, whereas Burning mouth syndrome (item 11) and Pain due to grinding teeth (item 10) showed the lowest frequency. The total number of experienced pain modalities closely correlated with the PDQ-8 index, but not with other variables. For all pain types except Pain around joints (item 1) and pain related to Periodic leg movements/RLS (item 7), patients with pain had significantly worse health-related quality of life. The influence of pain, as a whole, on the health-related quality of life was not remarkable after adjustment by other variables. When the particular types of pain were considered, adjusted by sex, age, and Parkinson's disease duration, pain determinants were different for EQ-5D-3L and PDQ-8. King's Parkinson's disease pain scale allows exploring the distribution of the diverse syndromic pain occurring in Parkinson's disease and its association with health-related quality of life.
eng
Distribution and impact on quality of life of the pain modalities assessed by the King's Parkinson's disease pain scale
research article
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File
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DistributionAndImpactOn_2017.pdf
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https://repisalud.isciii.es/bitstreams/5cd2675e-88f0-48f3-97f7-429f1a1acdd3/download
File
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text/plain
DistributionAndImpactOn_2017.pdf.txt