2026-07-26T16:09:13Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/143882025-05-30T12:39:24Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Medina, Narda author Rodriguez-Tudela, Juan Luis author Aguirre, Luis author Salazar, Luis R author Gamboa, Osmar author Bonilla, Oscar author Pérez, Juan C author Arathoon, Eduardo author Denning, David W author Alastruey-Izquierdo, Ana author 2021-12-16 Among people with HIV, histoplasmosis represents an important cause of mortality. Previous studies provided estimates of the disease incidence. Here, we compared those estimates with the results obtained from a screening program implemented in Guatemala, which included histoplasmosis detection for people with HIV. To compare the results of this program with previous estimations, a literature search was performed and reports concerning histoplasmosis incidence were analyzed. The screening program enrolled 6366 patients. The overall histoplasmosis incidence in the screening program was 7.4%, which was almost double that estimated in previous studies. From 2017 to 2019, the screening program showed an upward trend in histoplasmosis cases from 6.5% to 8.8%. Histoplasmosis overall mortality among those who were newly HIV diagnosed showed a decrease at 180 days from 32.8% in 2017 to 21.2% in 2019. The screening approach using rapid diagnostic assays detects histoplasmosis cases more quickly, allowing a specific treatment to be administered, which decreases the mortality of the disease. Therefore, the use of these new techniques, especially in endemic areas of histoplasmosis, must be implemented. Microorganisms. 2021 Dec 16;9(12):2596. 10.3390/microorganisms9122596 2076-2607 Microorganisms 34946197 http://hdl.handle.net/20.500.12105/14388 HIV Antigen Histoplasmosis Opportunistic infections Incidence of Histoplasmosis in a Cohort of People with HIV: From Estimations to Reality