2026-05-20T23:00:28Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/143422024-09-27T20:02:16Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Saez-Nieto, Juan Antonio
author
Carrasco, Gema
author
Pino-Rosa, Silvia del
author
Medina-Pascual, Maria Jose
author
Garrido, Noelia
author
Villalón, Pilar
author
Valdezate, Sylvia
2022-05-09T11:52:13Z
2022-05-09T11:52:13Z
2021-12
New Microbes New Infect. 2021 Dec 13;44:100946.
10.1016/j.nmni.2021.100946
2052-2975
New Microbes and New Infections
34917388
http://hdl.handle.net/20.500.12105/14342
Two hundred and eighty-six isolates from human clinical samples were identified between 1996 and 2019 as belonging to 8 families, 19 genera and 88 species of Actinobacteria. The most identified genera were Streptomyces (182 strains from 45 species), Actinomadura (29 strains, 5 species), Nocardiopsis (21 strains, 6 species) and Dietzia (18 strains, 5 species). The rest of the identified genera (15) contained 27 species with 36 isolates. Of the species studied, only 13/88 had been documented previously as isolates from clinical samples, and in some cases, as true pathogens. In this sense, a literature review of the species found in infections or in clinical samples without clear involvement in pathology has been carried out. Finally, the susceptibility to 8 antimicrobial agents has been studied. Streptomyces showed high resistance (80.8%) against cefotaxime and cotrimoxazole (55.5%), and no isolate resistance to amikacin and linezolid have been found. Lower percentages of resistance have been found in other genera, except in Dietzia (100% against cotrimoxazole and 44.4% against erythromycin). The greatest resistance in these genera was to cotrimoxazole (29.8) and erythromycin (27,9%), and no resistance to linezolid has been found in these genera. In Microbispora, Nonomuraea and Umezawaea, no resistant isolates have been found against any antibiotic studied. Only 3/104 isolates were resistant to amikacin in Amycolatopsis, Crossiella, and Micromonosopora. One isolate of Amycolatopsis was resistant to imipenem.
eng
Actimomadura
Actinobacteria
Streptomyces
Antimicrobial susceptibility
Human clinical samples
Identification and antimicrobial susceptibility of Streptomyces and other unusual Actinobacteria clinical isolates in Spain
journal article
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URL
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IdentificationAntimicrobialSusceptibilityStreptomyces_2021.pdf
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IdentificationAntimicrobialSusceptibilityStreptomyces_2021.pdf.txt