2026-08-29T14:12:12Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/143422024-09-27T20:02:16Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Saez-Nieto, Juan Antonio author Carrasco, Gema author Pino-Rosa, Silvia del author Medina-Pascual, Maria Jose author Garrido, Noelia author Villalón, Pilar author Valdezate, Sylvia author 2021-12 Two hundred and eighty-six isolates from human clinical samples were identified between 1996 and 2019 as belonging to 8 families, 19 genera and 88 species of Actinobacteria. The most identified genera were Streptomyces (182 strains from 45 species), Actinomadura (29 strains, 5 species), Nocardiopsis (21 strains, 6 species) and Dietzia (18 strains, 5 species). The rest of the identified genera (15) contained 27 species with 36 isolates. Of the species studied, only 13/88 had been documented previously as isolates from clinical samples, and in some cases, as true pathogens. In this sense, a literature review of the species found in infections or in clinical samples without clear involvement in pathology has been carried out. Finally, the susceptibility to 8 antimicrobial agents has been studied. Streptomyces showed high resistance (80.8%) against cefotaxime and cotrimoxazole (55.5%), and no isolate resistance to amikacin and linezolid have been found. Lower percentages of resistance have been found in other genera, except in Dietzia (100% against cotrimoxazole and 44.4% against erythromycin). The greatest resistance in these genera was to cotrimoxazole (29.8) and erythromycin (27,9%), and no resistance to linezolid has been found in these genera. In Microbispora, Nonomuraea and Umezawaea, no resistant isolates have been found against any antibiotic studied. Only 3/104 isolates were resistant to amikacin in Amycolatopsis, Crossiella, and Micromonosopora. One isolate of Amycolatopsis was resistant to imipenem. New Microbes New Infect. 2021 Dec 13;44:100946. 10.1016/j.nmni.2021.100946 2052-2975 New Microbes and New Infections 34917388 http://hdl.handle.net/20.500.12105/14342 Actimomadura Actinobacteria Streptomyces Antimicrobial susceptibility Human clinical samples Identification and antimicrobial susceptibility of Streptomyces and other unusual Actinobacteria clinical isolates in Spain