2026-05-22T00:39:50Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/143022025-06-09T11:07:34Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608
Repisalud
author
Mehdizadeh, Maryam
author
Martínez-Martín, Pablo
author
Habibi, Seyed-Amirhasan
author
Nikbakht, Negar
author
Alvandi, Faeze
author
Bazipoor, Parvane
author
Panahi, Ailin
author
Taghizadeh, Ghorban
funder
Tehran University of Medical Sciences (Irán)
2022-05-06T10:56:37Z
2022-05-06T10:56:37Z
2019-08
Basic Clin Neurosci. 2019;10(4):355-362.
10.32598/bcn.9.10.295
2008-126X
Basic and Clinical Neuroscience
32231772
http://hdl.handle.net/20.500.12105/14302
Introduction: In the elderly, functional balance, fear of falling, and independence in daily living activities are interrelated; however, this relationship may change under the influence of drug phase and the severity of disease in individuals with idiopathic Parkinson disease. This study aimed to investigate the association of functional balance, fear of falling, and independence in the Activities of Daily Living (ADL) with the drug on- and drug off-phases. Methods: A total of 140 patients with Parkinson disease (age: Mean±SD; 60.51±12.32 y) were evaluated in terms of their functional balance, fear of falling, and independence in their daily activities by the Berg Balance Scale (BBS), Fall Efficacy Scale-International (FES-I), and Unified Parkinson Disease Rating Scale-ADL (UPDRS-ADL), respectively, in drug on- and drug off-phases. The Hoehn and Yahr scale recorded global disease rating. The Spearman coefficient, Kruskal-Wallis, and Mann-Whitney tests were used to find out whether the distribution of scale scores differs with regard to functional balance or disease severity. Results: A strong correlation was found between the functional balance, fear of falling, and independence in ADL with both drug phases. The results also showed the significant difference in the distribution of the FES-I and UPDRS-ADL scores with regard to functional balance (except independence in ADL in drug off-phase). Also, the distribution of the scores of BBS, FES-I, and UPDRS-ADL showed significant differences with regard to disease severity. Conclusion: The study showed a strong correlation between functional balance, fear of falling, and independence in ADL that can be affected by the drug phase and severity of the disease. However, more studies are needed to understand this relationship precisely.
eng
Activities of daily living
Fear
Parkinson disease
Postural balance
The Association of Balance, Fear of Falling, and Daily Activities With Drug Phases and Severity of Disease in Patients With Parkinson
research article
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TheAssociationOfBalance_2019.pdf
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TheAssociationOfBalance_2019.pdf.txt