2026-06-14T03:31:50Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/142322024-09-27T19:50:10Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Vaccaro, Lucianna
author
Gomes, Thiago Santos
author
Izquierdo, Fernando
author
Magnet, Angela
author
Llorens Berzosa, Sergio
author
Ollero, Dolores
author
Salso, Santiago
author
Alhambra, Almudena
author
Gómez, Carmen
author
López Cano, María
author
Pelaz, Carmen
author
Bellido Samaniego, Beatriz
author
Del Aguila, Carmen
author
Fenoy, Soledad
author
Hurtado-Marcos, Carolina
funder
Instituto de Salud Carlos III
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Fundación Universitaria San Pablo CEU
funder
CEU San Pablo University
funder
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil)
2022-05-03T09:29:21Z
2022-05-03T09:29:21Z
2021-08
Front Microbiol. 2021;12:707187.
10.3389/fmicb.2021.707187
1664-302X
Frontiers in Microbiology
34413841
http://hdl.handle.net/20.500.12105/14232
L. feeleii is one of the most frequent Legionella species isolated from natural pools of the central region of Spain. This study aimed to evaluate its ecology and to identify this Legionella species as a respiratory pathogen. A PCR assay for detecting the L. feeleii mip gene was developed to identify it in clinical and environmental samples. Culture and PCR were performed in environmental samples from four drinking water treatment plants (DWTPs). Free L. feeleii was only detected in raw water samples (3.4%), while L. feeleii as an Acanthamoeba endosymbiont was found in 30.7% of raw water, 11.5% of decanter biofilm, and 32% of finished water samples. Therefore, Acanthamoeba spp. plays an essential role in the multiplication, persistence, and spread of Legionella species in the environment. The first case of Legionnaires' disease caused by L. feeleii in Spain is described in this study. The case was diagnosed in an older woman through PCR and sequencing from urine and sputum samples. A respiratory infection could be linked with health care procedures, and the patient presented several risk factors (age, insulin-dependent diabetes, and heart disease). The detection of non-L. pneumophila, such as L. feeleii, is a factor that must be considered when establishing or reviewing measures for the control and prevention of legionellosis.
eng
L. feeleii
Legionella
Legionnaires’ disease
Drinking water treatment plants
Molecular diagnosis
Legionella feeleii: Ubiquitous Pathogen in the Environment and Causative Agent of Pneumonia
research article
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