2026-06-14T03:32:35Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/142272024-09-27T18:39:34Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608
Repisalud
author
Di Gioia, María Cristina
author
Gallar Ruiz, Paloma
author
Cobo, Gabriela
author
Garcia Lopez, Fernando Jose
author
Agud Aparicio, José Luis
author
Oliet, Aniana
author
Rodríguez, Isabel
author
Ortega, Olimpia
author
Camacho, Rosa
author
Herrero, Juan Carlos
author
Mon, Carmen
author
Ortiz, Milagros
author
Vigil, Ana
2022-05-03T08:05:39Z
2022-05-03T08:05:39Z
2014
Enliven 2014; 1(1):1-7.
2378-542X
Enliven: Nephrology and Renal Studies
http://hdl.handle.net/20.500.12105/14227
Background: Overhydration, inflammation and protein-energy wasting have been related to all-cause mortality in dialysis patients, being lean mass loss, a poor prognostic factor. Objective: to monitor body composition changes (BCC) in hemodialysis (HD) patients and to relate BCC to mortality. Methods: Prospective follow up study: Bioimpedance spectroscopy (BIS) and nutritional parameters were performed every 6 months during three years. Results : Overall data show a significant loss of weight at 12m, 24m, and 36m, with decrease of lean tissue index and phase angle (PA) in each period measured. Fat tissue index (FTI) diminished in the third year’s measurements. End of first year, 41 % of patients gain weight, them at baseline had lower age, higher serum albumin, lower Extracelular/intracellular water index (ECW/ICW) and higher PA, showing a significant FTI increase. Higher baseline PA was gain weight predictor by binary logistic regression. Cox regression analyses: Age, diabetes, HD technique, albumin, ECW/ICW, and PA were mortality predictors in univariate analysis; being PA the main mortality predictor in multivariate analysis. BCC were not associated with mortality. ROC curve: PA higher than 4.85° is protective for mortality. Conclusions: Lean mass loss was the most important change during follow up; we have not observed association between BCC with mortality. PA was the main mortality predictor.
eng
Body composition
Bioimpedance spectroscopy
Hemodialysis
Mortality
Body Composition Changes in Hemodialysis Patients: Implications for Prognosis
journal article
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BodyCompositionChangesIn_2014.pdf
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BodyCompositionChangesIn_2014.pdf.txt