2026-04-30T06:56:22Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/142082025-06-17T07:08:49Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Alastruey-Izquierdo, Ana author Bonilla, Oscar author Ortíz, Brenan author Gamboa, Osmar author Salazar, Luis Roberto author Mercado, Danicela author Pérez, Juan C author Denning, David W author Arathoon, Eduardo author Rodriguez-Tudela, Juan Luis author Medina, Narda author Fungired author 2021-07 Objectives: To describe the impact of the coronavirus disease 2019 (COVID-19) pandemic on the diagnosis of human immunodeficiency virus (HIV) and deaths from opportunistic infections in Guatemala. Methods: A retrospective study was conducted to investigate the impact of the COVID-19 pandemic on people with HIV at a referral clinic (Clinica Familiar Luis Angel García, CFLAG), as well as the disruption of services at a diagnostic laboratory hub (DLH) which provides diagnosis for opportunistic infections to a network of 13 HIV healthcare facilities. Comparative analysis was undertaken using the months March-August from two different time periods: (i) pre-COVID-19 (2017-2019); and (ii) during the COVID-19 period (2020). Results: During the COVID-19 period, 7360 HIV tests were performed at Clinica Familiar Luis Angel García, compared with an average of 16,218 tests in the pre-COVID-19 period; a reduction of 54.7% [95% confidence interval (CI) 53.8-55.4%],Deaths from opportunistic infections at 90 days were 10.7% higher in 2020 compared with 2019 (27.3% vs 16.6%; P = 0.05). Clinical samples sent to the DLH for diagnosis of opportunistic infections decreased by 43.7% in 2020 (95% CI 41.0-46.2%). Conclusion: The COVID-19 pandemic is having a substantial impact on HIV care in Guatemala. Diagnostic services for HIV have been severely affected and deaths from opportunistic infections have increased. The lessons learnt must guide the introduction of strategies to reduce the impact of the pandemic. Int J Infect Dis. 2021;108:422-427. 10.1016/j.ijid.2021.06.011 1878-3511 International Journal of Infectious Diseases: IJID : official publication of the International Society for Infectious Diseases 34119676 http://hdl.handle.net/20.500.12105/14208 COVID-19 HIV testing Healthcare attention Opportunistic infections Impact of the COVID-19 pandemic on HIV care in Guatemala