2026-06-14T03:44:49Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/141722025-05-05T12:29:27Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16959col_20.500.12105_16962col_20.500.12105_16967col_20.500.12105_16968col_20.500.12105_16970col_20.500.12105_16974col_20.500.12105_16983

00925njm 22002777a 4500 dc Kogevinas, Manolis author Espinosa, Ana author Castelló Pastor, Adela author Gómez-Acebo, Inés author Guevara, Marcela author Martín, Vicente author Amiano, Pilar author Alguacil, Juan author Peiró, Rosana author Moreno, Victor author Costas, Laura author Fernández-Tardón, Guillermo author Jimenez, Jose Juan author Marcos-Gragera, Rafael author Perez-Gomez, Beatriz author Llorca, Javier author Moreno-Iribas, Conchi author Fernández-Villa, Tania author Oribe, Madalen author Aragones, Nuria author Papantoniou, Kyriaki author Pollan-Santamaria, Marina author Castaño-Vinyals, Gemma author Romaguera, Dora author 2018 Modern life involves mistimed sleeping and eating patterns that in experimental studies are associated with adverse health effects. We assessed whether timing of meals is associated with breast and prostate cancer risk taking into account lifestyle and chronotype, a characteristic correlating with preference for morning or evening activity. We conducted a population-based case-control study in Spain, 2008-2013. In this analysis we included 621 cases of prostate and 1,205 of breast cancer and 872 male and 1,321 female population controls who had never worked night shift. Subjects were interviewed on timing of meals, sleep and chronotype and completed a Food Frequency Questionaire. Adherence to the World Cancer Research Fund/American Institute of Cancer Research recommendations for cancer prevention was examined. Compared with subjects sleeping immediately after supper, those sleeping two or more hours after supper had a 20% reduction in cancer risk for breast and prostate cancer combined (adjusted Odds Ratio [OR] = 0.80, 95%CI 0.67-0.96) and in each cancer individually (prostate cancer OR = 0.74, 0.55-0.99; breast cancer OR = 0.84, 0.67-1.06). A similar protection was observed in subjects having supper before 9 pm compared with supper after 10 pm. The effect of longer supper-sleep interval was more pronounced among subjects adhering to cancer prevention recommendations (OR both cancers= 0.65, 0.44-0.97) and in morning types (OR both cancers = 0.66, 0.49-0.90). Adherence to diurnal eating patterns and specifically a long interval between last meal and sleep are associated with a lower cancer risk, stressing the importance of evaluating timing in studies on diet and cancer. Int J Cancer. 2018;143(10):2380-2389. 10.1002/ijc.31649 1097-0215 International Journal of Cancer http://hdl.handle.net/20.500.13003/17157 30016830 L623219591 2-s2.0-85050490115 http://hdl.handle.net/20.500.12105/14172 450113100007 Breast cancer Circadian disruption Diet Prostate cancer Effect of mistimed eating patterns on breast and prostate cancer risk (MCC-Spain Study)