2026-07-22T20:10:58Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/141132025-04-01T10:20:47Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19613col_20.500.12105_16990
Repisalud
author
Pinos, Helena
author
Carrillo, Beatriz
author
Merchán, Ana
author
Biosca-Brull, Judit
author
Pérez-Fernández, Cristian
author
Colomina, María Teresa
author
Sánchez-Santed, Fernando
author
Martin-Sanchez, Fernando
author
Collado, Paloma
author
Arias, Jorge L
author
Conejo, Nelida Maria
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Ministerio de Economía y Competitividad (España)
funder
Instituto de Salud Carlos III
2022-04-19T12:53:02Z
2022-04-19T12:53:02Z
2021-07-04
Int J Environ Res Public Health. 2021;18(13):7170.
10.3390/ijerph18137170
1660-4601
International Journal of Environmental Research And Public Health
34281107
http://hdl.handle.net/20.500.12105/14113
In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health.
eng
Carbamates
Chlorpyrifos
Neonicotinoids
Obesity
Organochlorine
Organophosphate
Pesticides
Pyrethroids
Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review
research article
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RelationshipBetweenPrenatalOr_2021.pdf
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RelationshipBetweenPrenatalOr_2021.pdf.txt