2026-07-21T14:14:05Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/141132025-04-01T10:20:47Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19613col_20.500.12105_16990

00925njm 22002777a 4500 dc Pinos, Helena author Carrillo, Beatriz author Merchán, Ana author Biosca-Brull, Judit author Pérez-Fernández, Cristian author Colomina, María Teresa author Sánchez-Santed, Fernando author Martin-Sanchez, Fernando author Collado, Paloma author Arias, Jorge L author Conejo, Nelida Maria author 2021-07-04 In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health. Int J Environ Res Public Health. 2021;18(13):7170. 10.3390/ijerph18137170 1660-4601 International Journal of Environmental Research And Public Health 34281107 http://hdl.handle.net/20.500.12105/14113 Carbamates Chlorpyrifos Neonicotinoids Obesity Organochlorine Organophosphate Pesticides Pyrethroids Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review