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                  <mods:namePart>González-Touya, Marta</mods:namePart>
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                  <mods:namePart>Sarria-Santamera, Antonio</mods:namePart>
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                  <mods:namePart>Nazarbayev University (Kazajstán)</mods:namePart>
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               <mods:identifier type="citation">Healthcare (Basel). 2021;9(7):873.</mods:identifier>
               <mods:identifier type="doi">10.3390/healthcare9070873</mods:identifier>
               <mods:identifier type="issn">2227-9032</mods:identifier>
               <mods:identifier type="journal">Healthcare (Basel, Switzerland)</mods:identifier>
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               <mods:abstract>Background: Diabetes mellitus is a significant public health problem. Macrovascular complications (stroke, acute myocardial infarction (AMI) and lower limb amputations (LLAs) represent the leading cause of morbi-mortality in DM. This work aims to evaluate the impact of the approval of the Diabetes Mellitus Strategy of the National Health System (SDM-NHS) on hospitalizations for those macrovascular complications related to DM. Methods: Interrupted time series applying segmented regression models (Negative Binomial) adjusted for seasonality to data from hospital discharge records with a primary or secondary diagnosis of DM (code 250 ICD9MC). Results: Between 2001 and 2015, there have been 7,302,750 hospital discharges with a primary or secondary diagnosis of DM. After the approval of the SDM-NHS, all the indicators showed a downward trend, modifying the previous trend in the indicators of AMI and LLA. The indicators of stroke and AMI also showed an immediate reduction in their rates. Conclusions: After the approval of the SDM-NHS, an improvement has been observed in all the indicators of macrovascular complications of DM evaluated, although it is difficult to establish a causal relationship between the strategy and the effects observed. Interrupted time series is applicable for evaluating the impact of interventions in public health when experimental designs are not possible.</mods:abstract>
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                  <mods:topic>Comorbidity</mods:topic>
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               <mods:subject>
                  <mods:topic>Diabetes mellitus</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Health plan implementation</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Interrupted time series</mods:topic>
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                  <mods:topic>Predictive and preventive strategies</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Public policies evaluation</mods:topic>
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               <mods:titleInfo>
                  <mods:title>Evaluating the Impact of the Diabetes Mellitus Strategy for the National Health System: An Interrupted Time Series Analysis</mods:title>
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