2026-06-14T03:46:55Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/139732025-05-08T10:38:30Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16969col_20.500.12105_16976

00925njm 22002777a 4500 dc Pato, Esperanza author Martín-Martínez, María Auxiliadora author Castelló Pastor, Adela author Méndez Fernandez, Rosalía author Muñoz-Fernández, Santiago author Cordero-Coma, Miguel author Martinez-Costa, Lucia author Valls, Elia author Reyes, Miguel author Francisco, Félix author Esteban, Mar author Fonollosa, Alex author Sánchez-Alonso, Fernando author Fernández-Espartero, Cruz author Diaz-Valle, Teresa author Carrasco, José Miguel author Beltran-Catalán, Emma author Hernández-Garfella, Marisa author Hernández, María Victoria author Pelegrin, Laura author Blanco, Ricardo author Díaz Valle, David author 2017-04 To develop a disease activity index for patients with uveitis (UVEDAI) encompassing the relevant domains of disease activity considered important among experts in this field. The steps for designing UVEDAI were: (a) Defining the construct and establishing the domains through a formal judgment of experts, (b) A two-round Delphi study with a panel of 15 experts to determine the relevant items, (c) Selection of items: A logistic regression model was developed that set ocular inflammatory activity as the dependent variable. The construct "uveitis inflammatory activity" was defined as any intraocular inflammation that included external structures (cornea) in addition to uvea. Seven domains and 15 items were identified: best-corrected visual acuity, inflammation of the anterior chamber (anterior chamber cells, hypopyon, the presence of fibrin, active posterior keratic precipitates and iris nodules), intraocular pressure, inflammation of the vitreous cavity (vitreous haze, snowballs and snowbanks), central macular edema, inflammation of the posterior pole (the presence and number of choroidal/retinal lesions, vascular inflammation and papillitis), and global assessment from both (patient and physician). From all the variables studied in the multivariate model, anterior chamber cell grade, vitreous haze, central macular edema, inflammatory vessel sheathing, papillitis, choroidal/retinal lesions and patient evaluation were included in UVEDAI. UVEDAI is an index designed to assess the global ocular inflammatory activity in patients with uveitis. It might prove worthwhile to motorize the activity of this extraarticular manifestation of some rheumatic diseases. Rheumatol Int. 2017;37(4):647-656 10.1007/s00296-016-3593-1 1437-160X Rheumatology International 27815703 http://hdl.handle.net/20.500.12105/13973 Activity index Ocular inflammation Outcome measures Uveitis Development of an activity disease score in patients with uveitis (UVEDAI)