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oai:repisalud.isciii.es:20.500.12105/139162024-11-29T09:39:50Zcom_20.500.12105_19604com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19605col_20.500.12105_16977

00925njm 22002777a 4500 dc Gómez-Talavera, Sandra author Fernandez-Jimenez, Rodrigo author Fuster, Valentin author Nothnagel, Nils D author Kouwenhoven, Marc author Clemence, Matthew author García-Lunar, Inés author Gómez-Rubín, María C author Navarro, Felipe author Pérez-Asenjo, Braulio author Fernández-Friera, Leticia author Calero, María J author Orejas, Miguel author Cabrera, José Ángel author Desco, Manuel author Pizarro, Gonzalo author Ibáñez, Borja author Sánchez-González, Javier author Nothnagel, Nils D. author Gómez-Rubín, María C. author Calero, María J. author Cabrera, José Ángel author 2021-09 This study sought to clinically validate a novel 3-dimensional (3D) ultrafast cardiac magnetic resonance (CMR) protocol including cine (anatomy and function) and late gadolinium enhancement (LGE), each in a single breath-hold. CMR is the reference tool for cardiac imaging but is time-consuming. A protocol comprising isotropic 3D cine (Enhanced sensitivity encoding [SENSE] by Static Outer volume Subtraction [ESSOS]) and isotropic 3D LGE sequences was compared with a standard cine+LGE protocol in a prospective study of 107 patients (age 58 ± 11 years; 24% female). Left ventricular (LV) mass, volumes, and LV and right ventricular (RV) ejection fraction (LVEF, RVEF) were assessed by 3D ESSOS and 2D cine CMR. LGE (% LV) was assessed using 3D and 2D sequences. Three-dimensional and LGE acquisitions lasted 24 and 22 s, respectively. Three-dimensional and LGE images were of good quality and allowed quantification in all cases. Mean LVEF by 3D and 2D CMR were 51 ± 12% and 52 ± 12%, respectively, with excellent intermethod agreement (intraclass correlation coefficient [ICC]: 0.96; 95% confidence interval [CI]: 0.94 to 0.97) and insignificant bias. Mean RVEF 3D and 2D CMR were 60.4 ± 5.4% and 59.7 ± 5.2%, respectively, with acceptable intermethod agreement (ICC: 0.73; 95% CI: 0.63 to 0.81) and insignificant bias. Both 2D and 3D LGE showed excellent agreement, and intraobserver and interobserver agreement were excellent for 3D LGE. ESSOS single breath-hold 3D CMR allows accurate assessment of heart anatomy and function. Combining ESSOS with 3D LGE allows complete cardiac examination in <1 min of acquisition time. This protocol expands the indication for CMR, reduces costs, and increases patient comfort. JACC Cardiovasc Imaging. 2021 Sep;14(9):1742-1754 10.1016/j.jcmg.2021.02.031 1876-7591 1936-878X JACC. Cardiovascular imaging 33865783 http://hdl.handle.net/20.500.12105/13916 Clinical Validation of a 3-Dimensional Ultrafast Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences.