2026-06-14T15:36:51Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/138432024-10-31T11:53:44Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Akuffo, Richard
author
Sanchez Herrero, Carmen
author
Chicharro, Carmen
author
Carrillo, Eugenia
author
Attram, Naiki
author
Mosore, Mba-Tihssommah
author
Yeboah, Clara
author
Kotey, Nana Konama
author
Boakye, Daniel
author
Ruiz-Postigo, Jose-Antonio
author
Moreno, Javier
author
Wilson, Michael
author
Sarfo, Bismark
author
Anto, Francis
funder
University of Ghana (Ghana)
funder
World Health Organization (WHO/OMS)
2022-03-28T09:40:17Z
2022-03-28T09:40:17Z
2021-05
PLoS Negl Trop Dis. 2021 May 24;15(5):e0009416.
10.1371/journal.pntd.0009416
1935-2735
PLoS Neglected Tropical Diseases
34029326
http://hdl.handle.net/20.500.12105/13843
Background: leishmaniasis (CL) is the most common type of leishmaniasis, a neglected tropical disease caused by parasites of the genus Leishmania. In Ghana, some studies in the Volta region have detected Leishmania parasites among persons with skin ulcers. Methodology/Principal findings: Using a cross-sectional study design, the prevalence of CL in three communities of the Oti Region of Ghana was investigated. Demographic and epidemiological data were obtained by a structured interviewer administered questionnaire. A total of 426 (12.4%) out of 3,440 participants screened had at least one skin ulcer. Of 595 skin ulcers sampled and tested by PCR for Leishmania infection, 150 (25.2%) ulcers from 136 individuals tested positive, accounting for an overall CL prevalence of 31.9% among persons with skin ulcers. Individual community CL prevalence of 23.2%, 29.8%, and 36.8% was observed in Ashiabre, Keri, and Sibi Hilltop respectively among persons with skin ulcers. Conclusions/Significance: Confirmation of CL in the study area suggests an active cycle of transmission of Leishmania infection. The observation of skin ulcers which tested negative to Leishmania infection suggests a need to test for additional causes of skin ulcers such as Treponema pallidum pertenue and Mycobacterium ulcerans in the study area.
eng
Cutaneous Leishmaniasis
Ghana
Lleishmaniasis
Tropical disease
Parasites
Detection of cutaneous leishmaniasis in three communities of Oti Region, Ghana
journal article
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