2026-06-14T15:36:51Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/138432024-10-31T11:53:44Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Akuffo, Richard author Sanchez Herrero, Carmen author Chicharro, Carmen author Carrillo, Eugenia author Attram, Naiki author Mosore, Mba-Tihssommah author Yeboah, Clara author Kotey, Nana Konama author Boakye, Daniel author Ruiz-Postigo, Jose-Antonio author Moreno, Javier author Wilson, Michael author Sarfo, Bismark author Anto, Francis author 2021-05 Background: leishmaniasis (CL) is the most common type of leishmaniasis, a neglected tropical disease caused by parasites of the genus Leishmania. In Ghana, some studies in the Volta region have detected Leishmania parasites among persons with skin ulcers. Methodology/Principal findings: Using a cross-sectional study design, the prevalence of CL in three communities of the Oti Region of Ghana was investigated. Demographic and epidemiological data were obtained by a structured interviewer administered questionnaire. A total of 426 (12.4%) out of 3,440 participants screened had at least one skin ulcer. Of 595 skin ulcers sampled and tested by PCR for Leishmania infection, 150 (25.2%) ulcers from 136 individuals tested positive, accounting for an overall CL prevalence of 31.9% among persons with skin ulcers. Individual community CL prevalence of 23.2%, 29.8%, and 36.8% was observed in Ashiabre, Keri, and Sibi Hilltop respectively among persons with skin ulcers. Conclusions/Significance: Confirmation of CL in the study area suggests an active cycle of transmission of Leishmania infection. The observation of skin ulcers which tested negative to Leishmania infection suggests a need to test for additional causes of skin ulcers such as Treponema pallidum pertenue and Mycobacterium ulcerans in the study area. PLoS Negl Trop Dis. 2021 May 24;15(5):e0009416. 10.1371/journal.pntd.0009416 1935-2735 PLoS Neglected Tropical Diseases 34029326 http://hdl.handle.net/20.500.12105/13843 Cutaneous Leishmaniasis Ghana Lleishmaniasis Tropical disease Parasites Detection of cutaneous leishmaniasis in three communities of Oti Region, Ghana