2026-07-23T20:40:18Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/138322024-11-29T09:25:10Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16974
Repisalud
author
Baré, Marisa
author
Montón, Concepción
author
Mora, Laura
author
Redondo, Maximino
author
Pont, Marina
author
Escobar, Antonio
author
Sarasqueta, Cristina
author
Fernandez de Larrea-Baz, Nerea
author
Briones, Eduardo
author
Quintana, Jose Maria
funder
Instituto de Salud Carlos III
funder
Unión Europea. Comisión Europea. European Research Council (ERC)
2022-03-28T07:22:39Z
2022-03-28T07:22:39Z
2017-04
Int J Chron Obstruct Pulmon Dis. 2017 Apr 21;12:1233-1241.
10.2147/COPD.S130377
1178-2005
International Journal of Chronic Obstructive Pulmonary Disease
28461746
http://hdl.handle.net/20.500.12105/13832
Background: We hypothesized that patients undergoing surgery for colorectal cancer (CRC) with COPD as a comorbidity would consume more resources and have worse in-hospital outcomes than similar patients without COPD. Therefore, we compared different aspects of the care process and short-term outcomes in patients undergoing surgery for CRC, with and without COPD. Methods: This was a prospective study and it included patients from 22 hospitals located in Spain – 472 patients with COPD and 2,276 patients without COPD undergoing surgery for CRC. Clinical variables, postintervention intensive care unit (ICU) admission, use of invasive mechanical ventilation, and postintervention antibiotic treatment or blood transfusion were compared between the two groups. The reintervention rate, presence and type of complications, length of stay, and in-hospital mortality were also estimated. Hazard ratio (HR) for hospital mortality was estimated by Cox regression models. Results: COPD was associated with higher rates of in-hospital complications, ICU admission, antibiotic treatment, reinterventions, and mortality. Moreover, after adjusting for other factors, COPD remained clearly associated with higher and earlier in-hospital mortality. Conclusion: To reduce in-hospital morbidity and mortality in patients undergoing surgery for CRC and with COPD as a comorbidity, several aspects of perioperative management should be optimized and attention should be given to the usual comorbidities in these patients.
eng
COPD
Colorectal cancer
Complications
In-hospital mortality
Reintervention
COPD is a clear risk factor for increased use of resources and adverse outcomes in patients undergoing intervention for colorectal cancer: a nationwide study in Spain
journal article
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URL
https://repisalud.isciii.es/bitstreams/5e5d7637-93a7-4ec2-a89d-91e6bb501eb6/download
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COPDIsAClear_2017.pdf
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https://repisalud.isciii.es/bitstreams/73c5cbc0-884d-4dde-9245-0039fa02ea59/download
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COPDIsAClear_2017.pdf.txt