2026-07-23T20:39:22Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/138322024-11-29T09:25:10Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16974

00925njm 22002777a 4500 dc Baré, Marisa author Montón, Concepción author Mora, Laura author Redondo, Maximino author Pont, Marina author Escobar, Antonio author Sarasqueta, Cristina author Fernandez de Larrea-Baz, Nerea author Briones, Eduardo author Quintana, Jose Maria author 2017-04 Background: We hypothesized that patients undergoing surgery for colorectal cancer (CRC) with COPD as a comorbidity would consume more resources and have worse in-hospital outcomes than similar patients without COPD. Therefore, we compared different aspects of the care process and short-term outcomes in patients undergoing surgery for CRC, with and without COPD. Methods: This was a prospective study and it included patients from 22 hospitals located in Spain – 472 patients with COPD and 2,276 patients without COPD undergoing surgery for CRC. Clinical variables, postintervention intensive care unit (ICU) admission, use of invasive mechanical ventilation, and postintervention antibiotic treatment or blood transfusion were compared between the two groups. The reintervention rate, presence and type of complications, length of stay, and in-hospital mortality were also estimated. Hazard ratio (HR) for hospital mortality was estimated by Cox regression models. Results: COPD was associated with higher rates of in-hospital complications, ICU admission, antibiotic treatment, reinterventions, and mortality. Moreover, after adjusting for other factors, COPD remained clearly associated with higher and earlier in-hospital mortality. Conclusion: To reduce in-hospital morbidity and mortality in patients undergoing surgery for CRC and with COPD as a comorbidity, several aspects of perioperative management should be optimized and attention should be given to the usual comorbidities in these patients. Int J Chron Obstruct Pulmon Dis. 2017 Apr 21;12:1233-1241. 10.2147/COPD.S130377 1178-2005 International Journal of Chronic Obstructive Pulmonary Disease 28461746 http://hdl.handle.net/20.500.12105/13832 COPD Colorectal cancer Complications In-hospital mortality Reintervention COPD is a clear risk factor for increased use of resources and adverse outcomes in patients undergoing intervention for colorectal cancer: a nationwide study in Spain