2026-06-14T03:43:16Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/134232024-09-27T09:23:37Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Lareo, Ana
author
Nuche, Jorge
author
Cristo Ropero, Maria J
author
Arribas-Ynsaurriaga, Fernando
author
Oliver, Eduardo
author
Escribano-Subias, Pilar
2021-10-04T08:47:15Z
2021-10-04T08:47:15Z
2021-04
Kardiol Pol. 2021; 79(4):386-392
10.33963/KP.15928
1897-4279
Kardiologia polska
33843179
http://hdl.handle.net/20.500.12105/13423
Pulmonary arterial hypertension (PAH) is a rare disease characterized by pulmonary vascular remodeling leading to increased vascular resistance. The increased afterload contributes to the development of right ventricular dysfunction and heart failure, which is the leading cause of death among patients with PAH. The development of specific treatments has markedly improved the prognosis of this population. However, PAH continues to be an incurable, life‑limiting condition, which creates a major burden for healthcare systems. This review describes the currently used treatments for PAH and provides insight into novel therapeutic targets that aim to reduce vascular remodeling, which ultimately leads to right ventricular failure.
eng
Recent advances in the pharmacotherapy of pulmonary hypertension: practical considerations.
journal article
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URL
https://repisalud.isciii.es/bitstreams/24a2b377-df15-435b-b58c-40b13d2b7881/download
File
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application/pdf
RecentAdvancesInThe_2021.pdf
URL
https://repisalud.isciii.es/bitstreams/b07df42b-50d0-4293-a4b4-d2215a564e50/download
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RecentAdvancesInThe_2021.pdf.txt