2026-07-21T19:37:29Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/131692024-11-28T14:50:31Zcom_20.500.12105_19604com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19605col_20.500.12105_16927col_20.500.12105_16961col_20.500.12105_16967col_20.500.12105_16968col_20.500.12105_16969col_20.500.12105_16982col_20.500.12105_16983col_20.500.12105_16989
Repisalud
author
Daimiel, Lidia
author
Martinez-Gonzalez, Miguel Angel
author
Corella, Dolores
author
Salas-Salvado, Jordi
author
Schroder, Helmut
author
Vioque, Jesus
author
Romaguera, Dora
author
Martinez, J Alfredo
author
Warnberg, Julia
author
Lopez-Miranda, Jose
author
Estruch, Ramon
author
Cano-Ibañez, Naomi
author
Alonso-Gómez, Angel
author
Tur, Josep A
author
Tinahones, Francisco J
author
Serra-Majem, Lluis
author
Mico-Perez, Rafael M
author
Lapetra, Jose
author
Galdon, Alba
author
Pinto, Xavier
author
Vidal, Josep
author
Mico, Victor
author
Colmenarejo, Gonzalo
author
Gaforio, Jose J
author
Matia, Pilar
author
Ros, Emilio
author
Buil-Cosiales, Pilar
author
Vazquez-Ruiz, Zenaida
author
Sorli, Jose V
author
Graniel, Indira Paz
author
Cuenca-Royo, Aida
author
Gisbert-Selles, Cristina
author
Galmes-Panades, Aina M
author
Zulet, M Angeles
author
Garcia-Rios, Antonio
author
Diaz-Lopez, Andres
author
de la Torre, Rafael
author
Galilea-Zabalza, Iñigo
author
Ordovas, Jose M
funder
International Nut and Dried Fruit Council
funder
California Walnut Commission
funder
Alexion Pharmaceuticals
funder
Sanofi
funder
Pfizer
funder
Amgen
funder
Fundación Cerveza y Salud
2021-06-22T05:32:29Z
2021-06-22T05:32:29Z
2020-02-28
Sci Rep. 2020; 10(1):3472
10.1038/s41598-020-59458-6
2045-2322
Scientific reports
http://hdl.handle.net/10668/15168http://hdl.handle.net/20.500.13003/11676
32103064
L631087643
2-s2.0-85080025325
http://hdl.handle.net/20.500.12105/13169
563209800009
Physical activity (PA) has been hypothesized to be effective to maintaining cognitive function and delay cognitive decline in the elderly, but physical fitness (PF) could be a better predictor of cognitive function. We aimed to study the association between PA and PF with cognitive function and quality of life using cross-sectional data from 6874 participants of the PREDIMED-Plus trial (64.9 ± 4.9 years, 48.5% female). PF and PA were measured with a Chair Stand Test, the REGICOR and Rapid Assessment Physical Activity questionnaires. Cognitive function was measured with Mini-mental State Examination, Control Oral Word Association Test, Trail Making Test and Digit Span tests; whereas health-related quality of life was assessed with the SF36-HRQL test. Cognitive and quality of life scores were compared among PF quartiles and PA levels (low, moderate and high) with ANCOVA and with Chair Stand repetitions and energy expenditure from total PA with multivariable linear regression adjusted for confounding factors. PF associated with higher scores in phonemic and semantic verbal fluency tests and with lower TMT A time. However, PA was not associated with the neurocognitive parameters evaluated. Both PF and PA levels were strongly associated with a better quality of life. We concluded that PF, but not PA, is associated with a better cognitive function. This trial was retrospectively registered at the International Standard Randomized Controlled Trial (ISRCTN89898870, https://www.isrctn.com/ISRCTN89898870?q=ISRCTN89898870&filters=&sort=&offset=1&totalResults=1&page=1&pageSize=10&searchType=basic-search) on 07/24/2014.
eng
Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial
research article
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