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                  <mods:namePart>Díaz, M Cristina</mods:namePart>
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                  <mods:namePart>Juliet L., Chrystal</mods:namePart>
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                  <mods:namePart>Rodriguez-Tudela, Juan Luis</mods:namePart>
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               <mods:identifier type="citation">Chil Infect 2004; 21 (1): 65-69</mods:identifier>
               <mods:identifier type="doi">10.4067/S0716-10182004000100010</mods:identifier>
               <mods:identifier type="e-issn">0716-1018</mods:identifier>
               <mods:identifier type="journal">Revista Chilena de Infectología</mods:identifier>
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               <mods:abstract>[ES] Se presenta el primer caso de infección por Scedosporium prolificans en nuestro país. Se trata de un paciente de 27 años, sexo masculino, con insuficiencia renal crónica e hipertensión, sometido a trasplante renal, en tratamiento con ciclosporina, azatioprina y prednisona. A los 25 días post-transplante presentó un aumento de volumen fluctuante bajo la herida operatoria. En tres muestras de exudado purulento y tejido obtenido finalmente por cirugía resolutiva se aisló S. prolificans como agente único. El estudio histológico reveló estructuras compatibles con hifas septadas. El paciente se trató con aseo quirúgico, anfotericina B e itraconazol lográndose la curación y cicatrización completa de la herida. S prolificans es un hongo filamentoso hialino resistente a anfotericina B y azoles, considerado actualmente un patógeno emergente, responsable de infecciones localizadas asociadas a cirugía y/o trauma, como también de infecciones diseminadas fatales en hospederos inmunocomprometidos especialmente pacientes neutropénicos, oncológicos y trasplantados. Es importante considerar este hongo en el diagnóstico diferencial de infecciones fúngicas emergentes.&#xd;
[EN] The aim of this article is to report the first case of infection by Scedosporium prolificans in our country. The patient corresponds to a 27 year-old man with chronic renal failure, hypertension, submitted to a renal transplant, in treatment with cyclosporine, azathioprine and prednisone. Twenty five days after the transplant, he noticed a fluctuating increase of volume under the surgical wound. In three consecutive purulent exudates and in tissue obtained at surgery, Scedosporium prolificans was isolated as an only agent. The histopathological study revealed structures compatible with septate hyphae. The patient was treated by surgical debridement, Amphotericin B and Itraconazol obtaining a complete cicatrization of the wound. S prolificans is a hyaline filamentous  fungi, resistant to Amphotericin B and azoles, considered currently an emerging pathogen. It is responsible of localized infections associated to surgery and/or trauma, as well as fatal disseminated infections in immunocompromised  hosts, specially oncological, in presence of neutropenia, and transplants. It is important to consider this microorganism in the differential diagnosis of emerging fungal infections.</mods:abstract>
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                  <mods:topic>Scedosporiumprolificans</mods:topic>
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                  <mods:title>Absceso de herida operatoria por Scedosporium prolificans: Primer aislamiento en Chile. Revisión de la literatura</mods:title>
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