2026-06-14T05:06:35Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/129362025-06-06T18:11:48Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Tapia, Cecilia
author
Gonzalez, Patricia
author
Díaz, M C
author
Corvalán, Valerie
author
Gaete, Marcela
author
Cuenca-Estrella, Manuel
author
Rodriguez-Tudela, Juan Luis
funder
Instituto de Salud Carlos III
funder
Agencia Española de Cooperación Internacional para el Desarrollo
funder
Hospital Dr. Sótero del Río
funder
University of Chile (Chile)
2021-05-12T09:12:25Z
2021-05-12T09:12:25Z
2002-06
Rev Med Chil. 2002 Jun;130(6):661-5.
0034-9887
Revista medica de Chile
12194689
http://hdl.handle.net/20.500.12105/12936
Background: Fungi are important causal agents of nosocomial infections, that usually have high mortality rates. Aim: To evaluate the species distribution and susceptibility patterns of deep yeast infections in a General Hospital and to correlate those results with patient survival. Material and methods: Twenty one strains (from five pediatric and 16 from adult patients) were studied. Antifungal Susceptibility Testing (AST) to Amphotericin B (Anfb), Fluorocytosine (5FC), Fluconazole (FZ) and Itraconazole (IZ) was performed according to the EUCAST document. Clinical data of patients was obtained and survival to the infection was recorded. Results: C. albicans was isolated in 11 samples (52%), C. parapsilosis in three samples (14%), C. glabrata in two samples (9%), C. tropicalis in one sample (5%) and C. neoformans in four samples (19%). Twenty three percent of fungi were recovered at the Surgical Intensive Care Unit. The MICs ranged between 0.25 and 0.5 microgram/mL for Anfb; between 0.25 and 16 micrograms/ml for SFC, between 0.12 and 32 micrograms/mL for FZ and 0.015 and 0.5 microgram/mL for IZ. No association between antifungal susceptibility and patient survival was observed. Conclusions: C. albicans continues to be the most frequently isolated yeast, however, non-albicans species are an emergent group causing nosocomial infections. Surgical procedures are the main source of fungal infections in this sample.
spa
Candidiasis
Candida albicans
Fungal count
Infection control
Infecciones sistémicas por levaduras en un hospital general. Correlación entre estudio de susceptibilidad in vitro y supervivencia de los pacientes al episodio de infección fúngica
research article
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InfeccionesSistémicasPorLevaduras_2002.pdf
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InfeccionesSistémicasPorLevaduras_2002.pdf.txt